DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and Kremen2

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	XP_017452551.1	Gene:	Kremen2 / 287102	RGDID:	1310795	Length:	468	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	66/307 - (21%)
Similarity:	96/307 - (31%)	Gaps:	82/307 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 LAADTFCQHSRERSATPIYSAGRLLGLRLRFQQPPT----------------------DLASWNL 169
            |.|..||::.........|.|....|:..|:...||                      ...|..|
  Rat    82 LGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKL 146

  Fly   170 TLNASYRFLKRENFR------------------TDGRLVPHSFCDFYFF---ASLSGEEANMG-- 211
            |:....||.:.:.::                  ..||..|.:.||...|   ..|.|.:..:|
  Rat   147 TVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIY 211

  Fly   212 --------------QGYFHSPQFPAHYPAHIKCAYKFIGRPDTHVEILFEELQLPPVVSGGCQLD 262
                          ||..:||.||..|.....|:: .:|:....:|:.|...:|..      ..|
  Rat   212 EVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSW-VLGQLGAVLELTFRLFELAD------SRD 269

  Fly   263 ALTLFDAESAHMNSVIDVICSSRPTRRLVSTGP------DLLLEFNASSNRTAKGFRGKYKFVSN 321
            .|.|.||.|.::....|......|       ||      .|||.|.:.:...|:||...|:.:.:
  Rat   270 RLELRDASSGNLLRAFDGAHPPPP-------GPLHLRTAALLLTFRSDARGHAQGFALTYRGLQD 327

  Fly   322 ---DLGVPNASVPPPAVLEAASVVVKQEKLQQEQASAAKENSLMSDV 365
               |...|..|....|.....:.|....|....|||...|..|.:.|
  Rat   328 TVEDRASPEDSAETLAGNPDGANVSCSPKPGAAQASIGGEADLQARV 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	36/147 (24%)
		CUB	<414..512	CDD:238001
		CUB	527..644	CDD:238001
Kremen2	XP_017452551.1	KR	33..118	CDD:214527	9/35 (26%)
		WSC	123..204	CDD:280068	12/80 (15%)
		CUB	218..323	CDD:238001	29/118 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910