DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34402 and Nrp1

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_659566.1	Gene:	Nrp1 / 246331	RGDID:	621588	Length:	922	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	76/330 - (23%)
Similarity:	118/330 - (35%)	Gaps:	93/330 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 LLLAKHALGGVVIGGSRVLQC-------------------------RYEFEAQAPE---RVQIRF 432
            ||.|..||...:.|..|..:|                         :.|:..||||   |:.|.|
  Rat     7 LLCATLALALALAGAFRSDKCGGTIKIENPGYLTSPGYPHSYHPSEKCEWLIQAPEPYQRIMINF 71

  Fly   433 ------------HDFNVPTEHENSTGCQPGDALHVVTELRGRYETQELLCGAFLPKPLMSSGQQL 485
                        :|:....:.||..|           .|.|::      ||...|.|::|||..|
  Rat    72 NPHFDLEDRDCKYDYVEVIDGENEGG-----------RLWGKF------CGKIAPSPVVSSGPFL 119

  Fly   486 HLQFVGKYPPTMTNKVQYYGFRAEYRFLTNFGIMSGIQKEG--CSFVYNSSERISGLFHSPNFPG 548
            .::||..|        :.:|        ..|.|...|.|.|  ||..|.:.   :|:..||.||.
  Rat   120 FIKFVSDY--------ETHG--------AGFSIRYEIFKRGPECSQNYTAP---TGVIKSPGFPE 165

  Fly   549 YYLENVVCNYYFYGASDERVVLHFTYFDIE------GIGSCDHQTASDYIE-FSNFMSTDRKFSR 606
            .|..::.|.|..:......::|.|..||:|      |...|.:    |.:| :..|........|
  Rat   166 KYPNSLECTYIIFAPKMSEIILEFESFDLEQDSNPPGGVFCRY----DRLEIWDGFPEVGPHIGR 226

  Fly   607 YCGKLPDFEMRSDGRFFRVTLHSNDRFVAIGFRALYTFETVSVNNSITDLR----DNASMQSFVS 667
            |||:.....:||......:..:::......||.|.|:....|::.....:.    ::..:.|...
  Rat   227 YCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSISEDFKCMEALGMESGEIHSDQI 291

  Fly   668 TASTQ 672
            |||:|
  Rat   292 TASSQ 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001
		CUB	<414..512	CDD:238001	27/137 (20%)
		CUB	527..644	CDD:238001	31/123 (25%)
Nrp1	NP_659566.1	CUB	27..140	CDD:238001	29/145 (20%)
		CUB	147..264	CDD:238001	31/123 (25%)
		FA58C	274..424	CDD:214572	5/23 (22%)
		FA58C	277..423	CDD:238014	5/20 (25%)
		FA58C	430..583	CDD:214572
		FA58C	435..582	CDD:238014
		MAM	645..804	CDD:214533
		MAM	650..803	CDD:99706
		DUF3481	842..919	CDD:152415
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910