DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34402 and sol-1

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_492088.3	Gene:	sol-1 / 172493	WormBaseID:	WBGene00004944	Length:	594	Species:	Caenorhabditis elegans

Alignment Length:	597	Identity:	164/597 - (27%)
Similarity:	241/597 - (40%)	Gaps:	129/597 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 FYFFASLSGEEA-----NMGQGYFHSPQFPAHYPAHIKCA-YKFIGRPDTHVEILFEELQLPPVV 255
            |.:|:..|..|.     |:..|.||||:|||.... :.|. |.|...||..:.:.|:..||||.:
Worm    17 FGYFSHASEHECKCVLFNVTSGNFHSPEFPAPLEG-VPCLFYHFQAPPDHIIRLTFDVFQLPPRI 80

  Fly   256 SGGCQLDALTLFD---------AESAHMNSVIDVICSSRPTRRLVSTGPDLLLEFNASSNRTAKG 311
             |.|. .::.|||         .|.|........|.|.   |:..|.....||:. :|...:::|
Worm    81 -GVCS-SSIMLFDHSTDGLIEFGERADFEFCGKEISSG---RQFFSKDQHFLLQI-SSGKESSRG 139

  Fly   312 FRGKYKFVSNDLGVPNASVPPPAV-LEAASVVVKQEK---------------------LQQEQAS 354
            |||.:      |.:|..:....|| :...|..|:::|                     :.|.:..
Worm   140 FRGSF------LAIPKKNFTSDAVEMAECSYRVEKQKAIIYSPDYPYYYPSKVNCTYHIPQRKGF 198

  Fly   355 AAKENSLMSDVELSKPGRSFEQCKQTFDSR-------VNKSGIFDSNQLLL---------AKHAL 403
            ....||::.|:......:.||..:..|:.|       |.||....|...||         .:.|:
Worm   199 QIVVNSIVMDIGRDAILQIFESVEGKFEKRLIEMVTSVQKSIYVSSTSSLLIYFSAGNNDVERAV 263

  Fly   404 GGVV-------------------------------------IG----GSRVLQCRYEFEAQAPER 427
            |.|:                                     ||    .|...:|:...:....|:
Worm   264 GFVIELQYSNAVWSQSPETASECQLNINSENFKEGQLSSDKIGRFTSSSLPTKCQIVLQGYPNEK 328

  Fly   428 VQIRFHDFN--VPTEHENSTGCQPGDALHVVTELRGRYETQELLCGAFLPKPLMSSGQQLHLQFV 490
            :.::|..||  ||.....:..|...|.|.....:..|....:..||...|..||||...|.|::.
Worm   329 ISVKFTHFNLYVPDNKNVTKRCTEVDNLSADVRVGSRLSRIDEWCGKRAPPNLMSSSNLLQLEYN 393

  Fly   491 GKYPPTM---TNKVQYYGFRAEYRFLT--NFGIMSG--IQKEGCSFVYNSSERISGLFHSPNFPG 548
            .|....:   ||  ...|||.:|:|.|  |.|.|..  .:|:.|.|.:||||..:|...|.|:||
Worm   394 TKSSKAIRESTN--DDIGFRLDYKFHTDWNMGNMKAKVDKKKECRFSFNSSEHTNGKLWSANYPG 456

  Fly   549 YYLENVVCNYYFYGASDERVVLHFTYFDIEGIGSCDHQTASDYIEFSNFMSTDRKFSRYCGK-LP 612
            .|..|:.|.|.|:|.:|:.|.:||.||||||...||..|.||||.|||:.:.||...|:||| .|
Worm   457 LYPRNLYCEYIFHGRNDQVVHIHFEYFDIEGFNQCDETTQSDYILFSNYQTHDRTNRRFCGKTAP 521

  Fly   613 DFEMRSDGRFFRVTLHSNDRFVAIGFRALYTFETVSVNNSITDLRDNASMQSFVSTASTQPVANV 677
            ...:.|:..:||:...:||.|.|.||.|.|.|        ||..:...|......::|..|.::.
Worm   522 KGPILSESNYFRMIFSTNDIFDATGFYAHYQF--------ITQEKSQISRVKLTISSSQTPFSSF 578

  Fly   678 NKLIACILCTYK 689
              .:..:|.|::
Worm   579 --FLVILLFTFR 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	41/135 (30%)
		CUB	<414..512	CDD:238001	27/102 (26%)
		CUB	527..644	CDD:238001	55/117 (47%)
sol-1	NP_492088.3	CUB	28..144	CDD:294042	37/122 (30%)
		CUB	298..416	CDD:238001	30/119 (25%)
		CUB	447..551	CDD:214483	48/103 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I4362
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122064
Inparanoid	1	1.050	162	1.000	Inparanoid score	I2843
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28734
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0017010
OrthoInspector	1	1.000	-	-		oto20760
orthoMCL	1	0.900	-	-		OOG6_114807
Panther	1	1.100	-	-	LDO	PTHR47537
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16956
SonicParanoid	1	1.000	-	-		X4379
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.000