DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34402 and CSMD2

DIOPT Version :9

Sequence 1:NP_001097756.1 Gene:CG34402 / 41513 FlyBaseID:FBgn0085431 Length:695 Species:Drosophila melanogaster
Sequence 2:NP_001268885.1 Gene:CSMD2 / 114784 HGNCID:19290 Length:3631 Species:Homo sapiens


Alignment Length:521 Identity:106/521 - (20%)
Similarity:168/521 - (32%) Gaps:144/521 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 FCDFYFFASLSGEEANMGQGYFHSPQFPAHYPAHIKCAYKFIGRPDTHVEILFEELQLPPVVSGG 258
            |..|:.|.|.|        |...||.:|..|..|:.|.:..:.||::.:.:.|.::.:.|     
Human   616 FSCFFNFTSPS--------GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----- 667

  Fly   259 CQLDALTLFDAESAHMNSVIDVICSSRPTRRLVSTGPDLLLEFNASSNRTAKGFRGKY-KFVSND 322
             |.|.|.:.|..:|.. .|:.....::....:.|:|....|||....:...:||...: .|..|:
Human   668 -QFDFLVIKDGATAEA-PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE 730

  Fly   323 LGVPNASVPPPAVLEAASVVVKQEKLQQEQASAAKENSLMSDVELSKPGRSFEQCKQTFDSRVNK 387
              .|:..||           |..::........:..:.|..:..|...|.....|       |.|
Human   731 --CPDPGVP-----------VNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITC-------VLK 775

  Fly   388 SGIFDSNQLLLAKHA-LGGVVIGGS-------------RVLQCRYEFEAQAPERVQIRFHDFNVP 438
            .|....|..:|...| .||.:...|             ..|.|.:..|||....::|.|..|...
Human   776 EGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTE 840

  Fly   439 TEHENSTGCQPGDALHVVTELRGRYETQELLCGAFLPKPLMSSGQQLHLQFVGKYPPTMTNKVQY 503
            ..::.   .:..|.......|.|.|.      |..:|:.|:|:...|:|.|       .|:|...
Human   841 VNYDT---LEVRDGRTYSAPLIGVYH------GTQVPQFLISTSNYLYLLF-------STDKSHS 889

  Fly   504 -YGFRAEYRFLT-------NFGIMSGIQKEG------------CSFVYNSS-------------- 534
             .||:..|..:|       :.||....|:.|            |...|..|              
Human   890 DIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWS 954

  Fly   535 --------------ERISGLFHSPNFPGYYLENVVCNYYFYGASDERVVLHFTYFDIEGIGSCDH 585
                          :..||...||.||.:|..|:.|.:....:..:.|...|..|.:|       
Human   955 RALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLE------- 1012

  Fly   586 QTASDYIEFSNFMSTDRKFSRYCG-KLP-------------------DFEMRSDGRFFRVTLHSN 630
             :..||:..:...|..:...:..| :||                   ||.|..:|  |.:|....
Human  1013 -SGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEG--FNITFSEY 1074

  Fly   631 D 631
            |
Human  1075 D 1075

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34402NP_001097756.1 CUB 195..318 CDD:238001 28/123 (23%)
CUB <414..512 CDD:238001 24/98 (24%)
CUB 527..644 CDD:238001 29/153 (19%)
CSMD2NP_001268885.1 CUB 66..173 CDD:238001
CCP 179..236 CDD:214478
CUB 242..345 CDD:238001
CCP 383..441 CDD:153056
CUB 445..553 CDD:278839
CCP 561..615 CDD:153056
CUB 618..725 CDD:238001 28/121 (23%)
CCP 731..789 CDD:153056 13/75 (17%)
CUB 792..899 CDD:238001 27/122 (22%)
CCP 907..961 CDD:153056 7/53 (13%)
CUB 964..1072 CDD:238001 25/117 (21%)
CCP 1079..1135 CDD:153056
CUB 1138..1245 CDD:238001
CCP 1251..1308 CDD:153056
CUB 1311..1419 CDD:238001
CCP 1425..1482 CDD:153056
CUB 1485..1590 CDD:278839
CCP <1595..>1687 CDD:332582
CUB 1659..1766 CDD:238001
CCP 1775..1833 CDD:153056
CUB 1836..1941 CDD:238001
CCP 1949..2005 CDD:153056
CUB 2008..2115 CDD:238001
Sushi 2121..2176 CDD:306569
CUB 2180..2286 CDD:238001
Sushi 2292..2349 CDD:306569
CUB 2357..2463 CDD:238001
CCP <2486..2642 CDD:332582
CCP 2609..2850 CDD:332582
CCP 2792..3032 CDD:332582
Sushi 3037..3091 CDD:306569
CCP 3091..3330 CDD:332582
CCP 3290..>3389 CDD:332582
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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