DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34402 and cubn

DIOPT Version :9

Sequence 1:NP_001097756.1 Gene:CG34402 / 41513 FlyBaseID:FBgn0085431 Length:695 Species:Drosophila melanogaster
Sequence 2:XP_012821080.2 Gene:cubn / 100125884 XenbaseID:XB-GENE-957007 Length:3631 Species:Xenopus tropicalis


Alignment Length:519 Identity:126/519 - (24%)
Similarity:186/519 - (35%) Gaps:104/519 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 FRTDGRLVPHSFCDFYFFASL---SGEEANMGQGYFHSPQFPAHYPAHIKCAYKFIGRPDTHVEI 244
            |.||.....|.|...|  .||   .|......||...||.:||.||..|:|.:.....|...:.:
 Frog   918 FTTDSSATNHGFSISY--QSLIEGCGGTLTDTQGTITSPGYPAVYPHGIQCTWFISIPPGNLIRL 980

  Fly   245 LFEELQLPPVVSGGCQLDALTLFDAESAHMNSVIDVICSSRPTRRLVSTGPDLLLEFNASSNRTA 309
            .|:...|....|  |..|.|.::|:.||.|.|.|...|.......:.|.|..:.:.....:|...
 Frog   981 TFDSFNLEHGYS--CSYDYLDIYDSASAIMESRIGRFCGRSIPPSITSRGNTMTVLLVTDTNTAV 1043

  Fly   310 KGFRGKYKFV-------------SNDLGVPNASVPPPAVLEAASVVVKQEKLQ----------QE 351
            :||..:|..:             |.....||.....|..||....:..:...|          ..
 Frog  1044 EGFSARYTSLNATTACDASYTEASGIFSSPNYPNRYPNNLECIYTITVETNKQILLNFTTFVLST 1108

  Fly   352 QASAAKENSLMSD--VELSKPGRSFEQ--------------CKQTFDSRVNKSGI---FDSNQLL 397
            ..:..|::..:.|  .|:|.....|.|              .|...||..:::|.   :||    
 Frog  1109 STNCDKDHVEIRDGGYEISPLLGKFCQGPPPVIVSHSNKLWVKFRSDSSYSETGFSAHWDS---- 1169

  Fly   398 LAKHALGGV---VIGG----------SRVLQCRYEFEAQAPERVQIRFHDFNVPTEHENSTGCQP 449
             |....||.   |.||          ....:|.::..|.:....:|:|..|::    |:.:.|| 
 Frog  1170 -ATTGCGGTLTSVSGGFTSPNFPMPYYHNSECYWQMMASSGSTFEIQFEHFDL----ESHSNCQ- 1228

  Fly   450 GDALHVVTELRGRYETQELLCGAFLPKPLMSSGQQLHLQFVGKYPPTMTNKVQYYGFRAEYRFLT 514
            .|.|.|...........|.|||..||.|:.|||..::::|      ...|.:.:.||.|.|    
 Frog  1229 NDYLAVYDGNTTHSHLLEKLCGKRLPDPIRSSGSNVYVKF------RTDNSISFSGFFATY---- 1283

  Fly   515 NFGIMSGIQKEGCSFVYNSSERISGLFHSPNFPGYYLENVVCNYYFYGASDERVVLHFTYFDIEG 579
                     |:.|..|. .:.|..|:..|.|:|..|..|..||:.........:...||.|::||
 Frog  1284 ---------KQTCQGVM-IANRSRGILESLNYPNSYPHNQQCNWTIQATLGNTINYTFTTFNVEG 1338

  Fly   580 IGSCDHQTASDYIEFSNFMSTD---RKFSRYCG-KLPDFEMRSDGRFFRVTLHSNDRFVAIGFR 639
            ..||     :||::.  :...|   |....||| :||. ...:.|....|..||:|.....||:
 Frog  1339 YFSC-----NDYVQL--YDGPDKQARLIGTYCGNQLPP-SGTTTGTSLHVVFHSDDTITRPGFQ 1394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34402NP_001097756.1 CUB 195..318 CDD:238001 34/125 (27%)
CUB <414..512 CDD:238001 27/97 (28%)
CUB 527..644 CDD:238001 34/117 (29%)
cubnXP_012821080.2 cubilin_NTD 28..133 CDD:412063
EGF_CA <138..166 CDD:238011
EGF_CA 169..210 CDD:238011
EGF_CA 262..305 CDD:214542
EGF_CA 306..349 CDD:214542
EGF_3 354..388 CDD:403986
EGF_CA 398..432 CDD:238011
EGF_CA 434..470 CDD:238011
CUB 476..589 CDD:238001
CUB 594..705 CDD:238001
CUB 712..821 CDD:395345
CUB 825..935 CDD:238001 6/18 (33%)
CUB 940..1052 CDD:238001 31/113 (27%)
CUB 1059..1167 CDD:238001 17/107 (16%)
CUB 1174..1283 CDD:238001 31/119 (26%)
CUB 1287..1399 CDD:238001 34/117 (29%)
CUB 1402..1515 CDD:238001
CUB 1521..1631 CDD:238001
CUB 1634..1749 CDD:238001
CUB 1754..1864 CDD:238001
CUB 1868..1976 CDD:238001
CUB 1994..2104 CDD:238001
CUB 2108..2228 CDD:238001
CUB 2233..2347 CDD:238001
CUB 2352..2461 CDD:238001
CUB 2468..2580 CDD:238001
CUB 2586..2702 CDD:238001
CUB 2705..2816 CDD:238001
CUB 2821..2931 CDD:238001
CUB 2933..3041 CDD:238001
CUB 3044..3154 CDD:395345
CUB 3164..3279 CDD:238001
CUB 3284..3399 CDD:238001
CUB 3402..3514 CDD:238001
CUB 3519..3631 CDD:238001
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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