DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD11 and EEF1G

DIOPT Version :9

Sequence 1:	NP_001138040.1	Gene:	GstD11 / 41512	FlyBaseID:	FBgn0038029	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	178	Identity:	42/178 - (23%)
Similarity:	74/178 - (41%)	Gaps:	31/178 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 PDFVAMNPQHCVPTM-NDEGLVLWESRAILSYLVAAYGKSDQLYPTDIRVRALVDQRLQFDLGTL 128
            |:|:...|...||.. .|:|..::||.||     |.|..:::|..:.....|.|.|.:.|....:
Human    47 PEFLRKFPAGKVPAFEGDDGFCVFESNAI-----AYYVSNEELRGSTPEAAAQVVQWVSFADSDI 106

  Fly   129 YMRLTDYYFPTMFI---GAPLDEGKRAKLAEAVGWLNTILEGRQFSAADHFTIADLTLLVTVSQL 190
            ....:.:.|||:.|   .....|..:.::...:|.|:..|:.|.|...:..|:||:|::.|:  |
Human   107 VPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTL--L 169

  Fly   191 EAFEFELRP-----YKHIRQWLDRC---------------KDHMAPFD 218
            ..::..|.|     :.:..:|...|               .:.||.||
Human   170 WLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFD 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD11	NP_001138040.1	GST_N_Delta_Epsilon	25..98	CDD:239343	11/33 (33%)
GstD11	NP_001138040.1	GST_C_Delta_Epsilon	112..231	CDD:198287	28/130 (22%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	13/39 (33%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	24/123 (20%)
		tolA	<212..>278	CDD:236545	4/6 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810