Protein Alignment STX19 and Syx17

DIOPT Version :10

• Sequence 1: NP_001001850.1
• Gene: STX19 / 415117
• HGNCID: 19300
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_001261414.1
• Gene: Syx17 / 38541
• FlyBaseID: FBgn0035540
• Length: 346
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 54/226 - (23%)
• Similarity: 92/226 - (40%)
• Gaps: 33/226 - (14%)

Human    67 NVQKFGQQQKSLVASMRRFSLLK-RESTITKEI------KIQAEYINRSLNDLVKEVKKSEVENG 124
            ::|:|..     ||.....|||| ..|.|.|.:      ||:.|.:|..  .::|::|...:|
  Fly    15 SIQRFQD-----VAVPHHLSLLKNHRSNIEKSLALGDWQKIKKEELNAM--RVIKQIKNLLLE-- 70

Human   125 PSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQG 189
                :..:.:.........|..:|....||..|..   |.|...||:.....:|.:..:|:.:|.
  Fly    71 ----MDALREKVREEDLERFDDLMKPGRDTAFAGM---KEFAELQLKSPTSTLSSQYDDDLDNQP 128

Human   190 KWEVFNESLLTEINITKAQLS------EIEQRH---KELVNLENQIKDLRDLFIQISLLVEEQGE 245
            : ||...||....::.:.||:      ::.||.   .::.||:.:|.||..:|..:..|..||..
  Fly   129 Q-EVDMNSLPAHRHMPQLQLNFQLEEHQLAQRQACLDQMENLQQEIYDLHGMFQGMRQLTAEQSV 192

Human   246 SINNIEMTVNSTKEYVNNTKEKFGLAVKYKK 276
            ::..|........|.|...:.....|:.|||
  Fly   193 AVEKIADNAEEALENVQQGELNLRRALTYKK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX19	NP_001001850.1	Syntaxin	49..244	CDD:459942	46/192 (24%)
		SNARE	212..278	CDD:473982	18/68 (26%)
Syx17	NP_001261414.1	SNARE_syntaxin17	156..217	CDD:277199	14/60 (23%)