DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD1 and EEF1E1

DIOPT Version :9

Sequence 1:	NP_001034042.1	Gene:	GstD1 / 41503	FlyBaseID:	FBgn0001149	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens

Alignment Length:	169	Identity:	46/169 - (27%)
Similarity:	73/169 - (43%)	Gaps:	28/169 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTL-VDNGFALWESRAIQVYLVEKYGKTDSL 83
            |.|..:.|.:|.|.|..|.....:     .:..||.| .:||.:|.....|..:||::..| :.|
Human     2 AAAAELSLLEKSLGLSKGNKYSAQ-----GERQIPVLQTNNGPSLTGLTTIAAHLVKQANK-EYL 60

  Fly    84 YPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEAFKK-IEAAFEFLNTFLEGQDY 147
            .....:::|::.|.|            .|...||      |..:.|. |....:.||::||.:.|
Human    61 LGSTAEEKAIVQQWL------------EYRVTQV------DGHSSKNDIHTLLKDLNSYLEDKVY 107

  Fly   148 AAGDSLTVADIALVATVSTF--EVAKFEISKYANVNRWY 184
            ..|.:.|:|||.|...:..|  ::...|..||.||:||:
Human   108 LTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWF 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD1	NP_001034042.1	GST_N_Delta_Epsilon	2..75	CDD:239343	15/55 (27%)
		GstA	4..185	CDD:223698	46/169 (27%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	28/99 (28%)
EEF1E1	NP_004271.1	N-terminal	2..56		16/58 (28%)
		Linker	57..63		2/6 (33%)
		C-terminal	64..152		28/101 (28%)
		GST_C_AIMP3	65..165	CDD:198338	28/100 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810