DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD1 and CLIC3

DIOPT Version :9

Sequence 1:	NP_001034042.1	Gene:	GstD1 / 41503	FlyBaseID:	FBgn0001149	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_004660.2	Gene:	CLIC3 / 9022	HGNCID:	2064	Length:	236	Species:	Homo sapiens

Alignment Length:	174	Identity:	38/174 - (21%)
Similarity:	69/174 - (39%)	Gaps:	37/174 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLK-INPQHTIPTLVDNGFALWESRAIQV 71
            |..| |:.:.|.....||......::.:.    .|:.|| ..|...:|.|:.:..|..::..|:.
Human    20 GHCPSCQRLFMVLLLKGVPFTLTTVDTRR----SPDVLKDFAPGSQLPILLYDSDAKTDTLQIED 80

  Fly    72 YLVEKYGKTD--SLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEA-FKKIEA 133
            :|.|..|..|  ||.|:..:.....|.        ::..|:.:....|    ||..|| ::::..
Human    81 FLEETLGPPDFPSLAPRYRESNTAGND--------VFHKFSAFIKNPV----PAQDEALYQQLLR 133

  Fly   134 AFEFLNTFLEG----------------QDYAAGDSLTVADIALV 161
            |...|:::|..                :.:..||.||:||.:|:
Human   134 ALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD1	NP_001034042.1	GST_N_Delta_Epsilon	2..75	CDD:239343	15/67 (22%)
		GstA	4..185	CDD:223698	38/174 (22%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	17/90 (19%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		16/71 (23%)
CLIC3	NP_004660.2	PLN02817	5..229	CDD:330276	38/174 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930