Protein Alignment GstD1 and CLIC3

DIOPT Version :10

• Sequence 1: NP_524326.1
• Gene: GstD1 / 41503
• FlyBaseID: FBgn0001149
• Length: 209
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 38/174 - (21%)
• Similarity: 69/174 - (39%)
• Gaps: 37/174 - (21%)

  Fly     9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLK-INPQHTIPTLVDNGFALWESRAIQV 71
            |..| |:.:.|.....||......::.:.    .|:.|| ..|...:|.|:.:..|..::..|:.
Human    20 GHCPSCQRLFMVLLLKGVPFTLTTVDTRR----SPDVLKDFAPGSQLPILLYDSDAKTDTLQIED 80

  Fly    72 YLVEKYGKTD--SLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEA-FKKIEA 133
            :|.|..|..|  ||.|:..:.....|.        ::..|:.:....|    ||..|| ::::..
Human    81 FLEETLGPPDFPSLAPRYRESNTAGND--------VFHKFSAFIKNPV----PAQDEALYQQLLR 133

  Fly   134 AFEFLNTFLEG----------------QDYAAGDSLTVADIALV 161
            |...|:::|..                :.:..||.||:||.:|:
Human   134 ALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLL 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD1	NP_524326.1	GST_N_Delta_Epsilon	2..75	CDD:239343	15/67 (22%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	17/90 (19%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		16/71 (23%)
		O-ClC	5..229	CDD:129941	38/174 (22%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		1/2 (50%)