Protein Alignment GstD1 and CLIC1

DIOPT Version :10

• Sequence 1: NP_524326.1
• Gene: GstD1 / 41503
• FlyBaseID: FBgn0001149
• Length: 209
• Species: Drosophila melanogaster
• Sequence 2: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 37/185 - (20%)
• Similarity: 62/185 - (33%)
• Gaps: 65/185 - (35%)

  Fly    63 LW-ESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYY------------Y 114
            || :.....|..|:...:|:::...||.     .|..:...||...:..|..            |
Human    34 LWLKGVTFNVTTVDTKRRTETVQKLCPG-----GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRY 93

  Fly   115 PQVFAKAP----ADPEAFKKIEA-------------------AFEFLNTFL-------------- 142
            |::.|..|    |..:.|.|..|                   |.:.|:.:|
Human    94 PKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAE 158

  Fly   143 -EG---QDYAAGDSLTVADIALVATVSTFEVA-----KFEISK-YANVNRWYENA 187
             ||   :.:..|:.||:||..|:..:...:|.     .|.|.: :..|:|:..||
Human   159 DEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNA 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD1	NP_524326.1	GST_N_Delta_Epsilon	2..75	CDD:239343	3/12 (25%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	30/158 (19%)
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		11/60 (18%)
		O-ClC	6..241	CDD:129941	37/185 (20%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27