Protein Alignment GstD9 and CLIC3

DIOPT Version :10

• Sequence 1: NP_650181.1
• Gene: GstD9 / 41502
• FlyBaseID: FBgn0038020
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 44/220 - (20%)
• Similarity: 68/220 - (30%)
• Gaps: 78/220 - (35%)

  Fly    13 CRSILMTARALGLELNKKQVDLDAGEHLKPEFVKINPQHTIPTLVDDGFAIWESRAILIYLAEKY 77
            |:.:.|.....|:......||......:..:|.   |...:|.|:.|..|..::..|..:|.|
Human    25 CQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFA---PGSQLPILLYDSDAKTDTLQIEDFLEE-- 84

  Fly    78 DKDGSLYPKD------------------------------PQQRAVINQRLFFDLSTLYQSYV-- 110
                :|.|.|                              |.|...:.|:|...|:.| .||:
Human    85 ----TLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARL-DSYLRA 144

  Fly   111 -----YYYYPQLFEDVKKPADPDNLKKIDDAFAMFNTLLKGQQYAALNKLTLADFALLATVSTFE 170
                 ....|||.|..::..|.|                         :|||||.:||..:...:
Human   145 PLEHELAGEPQLRESRRRFLDGD-------------------------RLTLADCSLLPKLHIVD 184

  Fly   171 ISEYDFGKYP------EVVRWYDNA 189
            .....|.:.|      .|.|:.|:|
Human   185 TVCAHFRQAPIPAELRGVRRYLDSA 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD9	NP_650181.1	GstA	1..187	CDD:440390	42/216 (19%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		15/71 (21%)
		O-ClC	5..229	CDD:129941	44/220 (20%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		44/220 (20%)