Protein Alignment MBD-R2 and BYE1

DIOPT Version :9

• Sequence 1: NP_731688.2
• Gene: MBD-R2 / 41498
• FlyBaseID: FBgn0038016
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: NP_012921.3
• Gene: BYE1 / 853865
• SGDID: S000001488
• Length: 594
• Species: Saccharomyces cerevisiae
• Alignment Length: 448
• Identity: 84/448 - (18%)
• Similarity: 142/448 - (31%)
• Gaps: 183/448 - (40%)

  Fly   881 INAALAPPPAETLSKAPQYIKENGELIRIVRMRQEEI-------INCIC----------EYGEED 928
            :::|:........|:.|:...||        :|.:|:       :.|:|          ||...|
Yeast    37 VDSAIEKNKKSDSSQEPRKDTEN--------VRTDEVDEADEGYVRCLCGANNENYDAAEYSHGD 93

  Fly   929 GLMIQCELCLCWQHGAC--------NGIVKEADVPDKYVCYIC---------------------- 963
              |:||:.|..|||..|        :|::.|   ..||.|.:|
Yeast    94 --MVQCDGCDTWQHIKCMTDGKDTIDGLMSE---DSKYYCELCDPSLYAHLETSKEAEVSEDEDY 153

  Fly   964 -------------------------RNPQRGRDS---MRFKHDQDWLFEG------KLPVAAYHT 994
                                     |..:|..||   :..|..|.....|      .:..|...|
Yeast   154 HDDVYKPVNDHDDNDADVFLDEESPRKRKRSPDSAKGIHIKSKQVKKSNGSKKRNKSIDAAKSDT 218

  Fly   995 A-NPQAT-KQFELLKRSHTLTGNLLDAKRSMHSLLVK--------------------INIARNRC 1037
            | |...| |.|| .::.|.|..|   |::...:|..|                    |:|::...
Yeast   219 AENEMPTRKDFE-SEKEHKLRYN---AEKMFSTLFSKFIVPETIEAKLYELPDGKDVISISQEFA 279

  Fly  1038 H------------------PKLY------LWAKKWDEDNLDSTA-----------LTPVKRAKLE 1067
            |                  .|:|      |::...|:.||:..|           |..:..::|.
Yeast   280 HNLEEELYKACLNVEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNKLVNMNASELA 344

  Fly  1068 APDLPNVPQPEAAI--------DPEECQY-------RLIEHIKVQQ--------SLVLDRLNDIE 1109
            .|||....:....|        .|::..|       .|||.|...|        |:.|..::.|:
Yeast   345 NPDLQEFKEKRDKIILENFIVEVPDKPMYVKTHKGDELIEDIAEPQEDILYSKDSIRLHNIDSID 409

  Fly  1110 AEMDELEKEDTLDDLKDADIST--TKEAL-ATFIKELETMKRLAKLNQVANMKQTLRD 1164
            ::..::|:...:.  |:...||  .:|:| ..|:.....::....||.:...::..||
Yeast   410 SDKSKIEQTHAIS--KEPSPSTIINEESLNCAFLYPGLGLEFTGYLNYIGASQKLRRD 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	4..86	CDD:283206
		TUDOR	292..329	CDD:119391
		MeCP2_MBD	449..522	CDD:238690
		PHD_SF	919..963	CDD:304600	18/61 (30%)
BYE1	NP_012921.3	PHD_Bye1p_SIZ1_like	74..131	CDD:277045	18/61 (30%)
		TFS2M	235..354	CDD:128786	21/121 (17%)
		SPOC	434..589	CDD:400205	7/32 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030