Protein Alignment MBD-R2 and Mbd4

DIOPT Version :9

• Sequence 1: NP_731688.2
• Gene: MBD-R2 / 41498
• FlyBaseID: FBgn0038016
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: XP_001059437.3
• Gene: Mbd4 / 680915
• RGDID: 1585874
• Length: 566
• Species: Rattus norvegicus
• Alignment Length: 457
• Identity: 100/457 - (21%)
• Similarity: 162/457 - (35%)
• Gaps: 140/457 - (30%)

  Fly   399 PLLDMASLDIASLGLPEIPHDGEWTCHWVNDQPIGTE-GFLI-------------VGEHQKPTVI 449
            |..|....|:| :||..:..||:       |..|.:| |.|:             |.|..||
  Rat    24 PPWDRCKEDVA-VGLGGVGEDGK-------DLVISSECGSLLQEPAASTLPSCTTVAECHKP--- 77

  Fly   450 VQDWRLPPGWIKHMYQR--SNVLGKWDVILVSPSGKRFRSKSDL-KLFLESQNLVYNPDVYDFSI 511
                 :|.||.:.:.||  ....|:.||..:||.|.:||||..| ...|::......|:.:||::
  Rat    78 -----VPCGWERVVKQRLSGKTAGRVDVYFISPQGSKFRSKRSLANYLLKTGETCLKPEDFDFTV 137

  Fly   512 HRRRAKDINAYVYTHGYNPQ---PPPKPRPMDVSMNSTLDQSITSQHSLPSTPMPVKESQYMEAP 573
            ..:..  ||.     ||..|   .|...:|.:..: |.|:....|:......|:|...|:..::.
  Rat   138 LSKGG--INP-----GYKHQSLSAPASQQPNEADI-SKLNLRTRSKWKTDVLPLPGGNSESPDSN 194

  Fly   574 VASLMPPAELMSPQ---TQPAD---ETKPKIEAEILE--ASEGGTSQLMLADPH----------- 619
            ..|....|.|:..:   .|.||   ..||||:..:|:  ||: .|.|.....|.
  Rat   195 SLSNSNSARLLLKEHKGIQDADSGKSRKPKIKVTVLKGIASQ-RTKQRCRKSPSDSTGRNRKRLC 258

  Fly   620 VVENGFAFIGGLKVKIQDNLY--VCPREDCA---------------------------------- 648
            .|:.  |......|..:..|:  |||.:.||
  Rat   259 TVQK--ADTDSELVPQESRLHRTVCPADACARATVSLVREAKGLGEEKSPSSDLRFTQVTSSITN 321

  Fly   649 KTY-------------RKEDFL-LIHIR--------HYHKEFAEHVSHCPKMQELAVKRTHPSSI 691
            |.|             |::.|| ...||        |.|.:..:..|..|...:  .|:...|..
  Rat   322 KLYSTEAAGEATREATREQTFLESEEIRSKGEEEEAHLHIDILQSGSETPSCSQ--AKKHLTSET 384

  Fly   692 DQVEAVPKNQIPNQQ----FFAKMHQQDLQQSRSFKRQSVSATATSSTPSDIT-------PTKAL 745
            .:.:::|:.|:..::    |.:|.:::.|...|   |::........:|.::.       |.|.|
  Rat   385 FREDSIPRTQVEKRKTSLYFSSKYNKEALSPPR---RKAFKKWTPPRSPFNLVQETLFHDPWKLL 446

  Fly   746 LS 747
            :|
  Rat   447 IS 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	4..86	CDD:283206
		TUDOR	292..329	CDD:119391
		MeCP2_MBD	449..522	CDD:238690	22/75 (29%)
		PHD_SF	919..963	CDD:304600
Mbd4	XP_001059437.3	MeCP2_MBD	77..149	CDD:238690	25/86 (29%)
		ENDO3c	436..>522	CDD:304925	4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I11890
eggNOG	1	0.900	-	-		E1_KOG4161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900