Protein Alignment MBD-R2 and MBD-like

DIOPT Version :10

• Sequence 1: NP_731688.2
• Gene: MBD-R2 / 41498
• FlyBaseID: FBgn0038016
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: NP_001262421.1
• Gene: MBD-like / 41151
• FlyBaseID: FBgn0027950
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 61/256 - (23%)
• Similarity: 89/256 - (34%)
• Gaps: 70/256 - (27%)

  Fly   151 TGKAADDVKN---TPESGEDANKAAAKEPSGTPVAASSEATVPAPGSASSSNSPLPGTPPKYSNP 212
            :|.||:.:|.   ..:.|..|..|.|..|:.|   |||.||..|   ||:|    |.|..:....
  Fly   120 SGSAANALKRKFARSQGGNAAGAAGAAPPAAT---ASSAATATA---ASAS----PSTANRQQQQ 174

  Fly   213 HNLTIGARLEALSVEGNWLPARIVEVNETEQTLL--VRFERNHKLKVSPSTSGSFQEWMAIKSER 275
            ..|:     .||..:.:.:|    .:.:|.....  |...||||           |:....|:|
  Fly   175 IELS-----RALRTDVSLVP----PIRQTASIFKQPVTVIRNHK-----------QDPAKAKNE- 218

  Fly   276 LRQRLSNRVLPVFELDEKCMARWSGPRKFPGTIRKLLGNDTYEVLFDDGYVKNVRAVHMNKMPKQ 340
              .:...|..|.....||.:.|          :|..  :|:.|.|.|....|.:|.|..|
  Fly   219 --PKHGTREKPKQLFWEKRLER----------LRAC--HDSGEELDDISLPKTIRTVGPN----- 264

  Fly   341 LPPVQVAEEGASKSPTPVGTPVSSAPVAPKRASTGSLGGSSGSSGSKKSKCAPQRRDWPLL 401
                 |.|:          |.:.|...|....:.|..|.||..:...|:..|....:.||:
  Fly   265 -----VNEQ----------TVLQSVATALHMLNAGVHGQSSTKADLTKNAMAFMNPEQPLM 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	5..84	CDD:461662
		MBT_PHF20L1-like	215..282	CDD:439094	13/68 (19%)
		Tudor_PHF20-like	288..337	CDD:410457	12/48 (25%)
		MeCP2_MBD	449..522	CDD:238690
		PHD_SF	919..963	CDD:473978
		PRK04778	<1099..>1153	CDD:179877
MBD-like	NP_001262421.1	MBD	9..101	CDD:396147
		MBDa	171..241	CDD:465179	18/102 (18%)
		MBD_C	245..338	CDD:464072	20/86 (23%)