DRSC/TRiP Functional Genomics Resources

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Protein Alignment MBD-R2 and mbd3a

DIOPT Version :9

Sequence 1:NP_731688.2 Gene:MBD-R2 / 41498 FlyBaseID:FBgn0038016 Length:1169 Species:Drosophila melanogaster
Sequence 2:NP_997934.1 Gene:mbd3a / 337133 ZFINID:ZDB-GENE-030131-9077 Length:273 Species:Danio rerio


Alignment Length:286 Identity:63/286 - (22%)
Similarity:105/286 - (36%) Gaps:74/286 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   455 LPPGWIKHMYQRSNVL--GKWDVILVSPSGKRFRSKSDLKLFL-ESQNLVYNPDVYDF------- 509
            ||.||......|.:.|  ||.||...||:||:||||..|..:| :|.:|    ..:||       
Zfish    11 LPNGWKMEEVTRKSGLSAGKSDVYYFSPTGKKFRSKPQLVRYLGKSMDL----SSFDFRTGKMLM 71

  Fly   510 ---SIHRRRAKDINAYVYTHGYNPQPPPKPRPMDVSMNSTL-DQSITSQHSLPSTPMPVKESQYM 570
               :.:|:|.:.      .|..|...|.....:.|...::: .|.:|...:.||..:.....:.:
Zfish    72 SKLNKNRQRIRS------DHSQNKGKPDLNTSLPVRQTASIFKQPVTKVTNHPSNKVKTDPQKAV 130

  Fly   571 EAP---------------------VASLMPPAELMSPQTQPADETKPKIEAEILEASEGG-TSQL 613
            |.|                     |.::..|..|.......:|:|.....|..|..|... |.||
Zfish   131 EQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGYSDKTLLSALASALHTSSAPITGQL 195

  Fly   614 MLADPHVVENGFAFIGGLKVKIQDNLYVCPREDCAKTY-------RKEDFLLIHIRHYHKE--FA 669
            ..|                |:....:::...:...|::       ||::.|:.::|...:|  .|
Zfish   196 SAA----------------VEKNPGVWLNTTQPLCKSFMVTDEDIRKQEDLVFNVRKRLEEALMA 244

  Fly   670 EHVSHCPKMQELAVKRTHPSSIDQVE 695
            :.::|   ::|.|.....|.|.|..|
Zfish   245 DMLAH---IEEAAGDDKKPLSEDSAE 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MBD-R2NP_731688.2 THAP 4..86 CDD:283206
TUDOR 292..329 CDD:119391
MeCP2_MBD 449..522 CDD:238690 26/79 (33%)
PHD_SF 919..963 CDD:304600
mbd3aNP_997934.1 MeCP2_MBD 5..78 CDD:238690 24/70 (34%)
MBDa 87..147 CDD:293172 9/59 (15%)
MBD_C 152..242 CDD:290755 19/105 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4161
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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