Protein Alignment MBD-R2 and Y73B3A.1

DIOPT Version :9

• Sequence 1: NP_731688.2
• Gene: MBD-R2 / 41498
• FlyBaseID: FBgn0038016
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: NP_508081.2
• Gene: Y73B3A.1 / 180384
• WormBaseID: WBGene00022203
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 104/559 - (18%)
• Similarity: 178/559 - (31%)
• Gaps: 216/559 - (38%)

  Fly   531 QPPPKPRPMDVSM---------------------------NSTLDQSITSQ--HSLPSTPMPVKE 566
            ||||:.:..:::.                           |..:|..:.:|  :..|..|.|
 Worm    17 QPPPQQQQPEIAEPIVMAQEPIQGVSEDPQASEATHEAPDNYPVDHQMENQEFYQEPQIPEP--- 78

  Fly   567 SQYMEAPVASLMPPA-----ELMSPQTQ-------PADETKPKIEAEILEASEGGTSQLMLAD-- 617
               .:.|..|:..||     ..::||.:       .|.:.:|..|.|.| |:||.|:.....|
 Worm    79 ---QQIPQISVFQPAAYNPSNYVAPQQRANNFGEPAAADARPLTEEEQL-AAEGPTADTAWIDSD 139

  Fly   618 ----------------PH----------------VVENGFAFIGGLKVKIQDNLYVCPREDC--A 648
                            |:                ..|..|..|.||.            |||  .
 Worm   140 DDTDVEEAILRANFWLPYSDHNYDPPDPADRIILPTEGPFPCIAGLD------------EDCNIV 192

  Fly   649 KTYRKEDFL------LIHIRHYHKEFA-EHVSHCPKMQELAVKR---------THPSSI--DQVE 695
            |.:..||.:      ..:.|:...... ...|..|:.|:|.|:.         ..|.||  :|||
 Worm   193 KQWMPEDAVGPGSPGTQYRRNQQTGGGLPSTSVAPQQQQLPVRHNIQNRPMVAAQPFSIGGNQVE 257

  Fly   696 -------------------------------AVP-KNQIPNQQ--FFAKMHQQDLQQ-------- 718
                                           .:| :.|:|...  ..|...::|..:
 Worm   258 YGGIGGMDSRMQQRGVVRDGPQYRVMNDFGNGLPMRGQLPRNSPAANATAAREDAPEASIPAPAP 322

  Fly   719 SRSFKRQSVSATATSSTPSDITPT---------KALLSPKMEP--------------PSVSPTVE 760
            |....|:|||.|...||.|..|||         :.::.||.||              .:|....|
 Worm   323 SPPASRRSVSRTTQPSTSSFATPTEPPAKNQRKRRVVPPKSEPVLSAKRVRATEAKKKAVEKVKE 387

  Fly   761 SGIKQEDVSLDAGPTQSFNPSLSRSCKRARLSPSKRPSGSRKSNRQRSQRRPILSDNPAGHGLTE 825
            ...|::....::||.    |...::.::|.....|:|...:|...:.:.::|.|.......|: |
 Worm   388 KEKKEQRKPNESGPA----PKSEKAVEKAEEKVEKKPKSPQKPPAKPTAQKPPLKKTEEVDGI-E 447

  Fly   826 QDVEETRQSFNTPTPDTR------------IDSKKRRSGAATTP--------ISSIDSP------ 864
            ::..|:....::..|:.:            ..|:||::|..:||        |.|.:..
 Worm   448 REASESSSKKSSVAPEKKNPKKIAFVEYNSRSSRKRKAGECSTPPAVTRRGFIPSTEGEDLENVE 512

  Fly   865 ----AMGDSVSTPSSNDQTDINAAL--APPPAETLSKAP 897
                .:.|.:|:.::...|.|..::  ||.|...:.|:|
 Worm   513 LSVIPLDDHLSSSNTAPTTTIAPSVGGAPKPTSVVVKSP 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	4..86	CDD:283206
		TUDOR	292..329	CDD:119391
		MeCP2_MBD	449..522	CDD:238690
		PHD_SF	919..963	CDD:304600
Y73B3A.1	NP_508081.2	PRK03427	<9..>132	CDD:235124	25/121 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1844
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900