DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MBD-R2 and C16A11.4

DIOPT Version :9

Sequence 1:	NP_731688.2	Gene:	MBD-R2 / 41498	FlyBaseID:	FBgn0038016	Length:	1169	Species:	Drosophila melanogaster
Sequence 2:	NP_494744.2	Gene:	C16A11.4 / 173755	WormBaseID:	WBGene00015817	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	141	Identity:	30/141 - (21%)
Similarity:	52/141 - (36%)	Gaps:	28/141 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   876 NDQTDINAALAPPPAETLSKAPQYIKENGELIRIVRMRQEEIINCICEYGEEDGLMIQCELCLCW 940
            :|.::......||||         |:::...:..:...|:| :.|.|.....|..:|:|..|..|
Worm     2 DDSSEEANQFEPPPA---------IRKSTRAVNNLSPHQKE-VRCQCGTNNTDNRLIKCVECEKW 56

  Fly   941 QHGACNGIVKEADVPDKYVCYICRNPQRGRDSMRFKHDQDWLFEGKLPVAAYHTANPQATKQFEL 1005
            ||..|..:: ..|:...|.|.:|              :...|...:....||....|:..   |:
Worm    57 QHAICMSVM-PLDIIMTYKCEMC--------------EPRLLMVSRSQARAYQGVEPEPR---EV 103

  Fly  1006 LKRSHTLTGNL 1016
            .|:....:.||
Worm   104 RKKGRNQSVNL 114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	4..86	CDD:283206
		TUDOR	292..329	CDD:119391
		MeCP2_MBD	449..522	CDD:238690
		PHD_SF	919..963	CDD:304600	13/43 (30%)
C16A11.4	NP_494744.2	PHD_SF	35..78	CDD:389947	13/43 (30%)
C16A11.4	NP_494744.2	SPK	117..221	CDD:367941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030