Protein Alignment MBD-R2 and PHF13

DIOPT Version :10

• Sequence 1: NP_731688.2
• Gene: MBD-R2 / 41498
• FlyBaseID: FBgn0038016
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: XP_011539064.1
• Gene: PHF13 / 148479
• HGNCID: 22983
• Length: 309
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 59/262 - (22%)
• Similarity: 92/262 - (35%)
• Gaps: 71/262 - (27%)

  Fly   748 PKMEPP---SVSPTVESGIKQEDVSLDAG----------PTQS-----FNPSLSRSCKRARLSPS 794
            ||.|.|   |.||...:....:....|||          |...     ..|:|.:..|.:.....
Human    54 PKEELPLRSSPSPANSTAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLD 118

  Fly   795 KRPSGSRKSNRQRSQRRPILSDNPAGHGLTE--QDVEETRQSFNTPTPDTRIDSKKRRSGAATTP 857
            ::.:...|..::|.:|.   ||.|...|...  ..:|.......|||..|..|..:    |.:.|
Human   119 RKKTDKLKKKKKRKRRD---SDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQ----APSDP 176

  Fly   858 ISSIDSPAMGDSVSTPSSNDQTDINAALAPPPAETLSKAPQYIKENGELIRIVRMRQE------- 915
            .|..||       .||||..    .|.::|...:.       ||..|:. .|||..::
Human   177 CSGWDS-------DTPSSGS----CATVSPDQVKE-------IKTEGKR-TIVRQGKQVVFRDED 222

  Fly   916 -----------------EIINCICEYGEEDGLMIQCELCLCWQHGACNGIVKEADVPDKYVCYIC 963
                             :::.|.|........||:|..|..|.|.:| ..:::::||:.:||..|
Human   223 STGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSC-AKIRKSNVPEVFVCQKC 286

  Fly   964 RN 965
            |:
Human   287 RD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-R2	NP_731688.2	THAP	5..84	CDD:461662
		MBT_PHF20L1-like	215..282	CDD:439094
		Tudor_PHF20-like	288..337	CDD:410457
		MeCP2_MBD	449..522	CDD:238690
		PHD_SF	919..963	CDD:473978	13/43 (30%)
		PRK04778	<1099..>1153	CDD:179877
PHF13	XP_011539064.1	PHD_PHF13	241..287	CDD:277102	13/46 (28%)