DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10041 and CG18754

DIOPT Version :9

Sequence 1:	NP_650177.2	Gene:	CG10041 / 41496	FlyBaseID:	FBgn0038014	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	75/290 - (25%)
Similarity:	105/290 - (36%)	Gaps:	97/290 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PLLATTVSTTKVISFRPR---------YPYIVSIGENLKGYYKHLCVGVILSNEFVLSAAHCIQT 87
            |...|...||.|  ||.|         ||::|     |..|...|.:     ..:||:||||
  Fly    92 PNKQTCGQTTPV--FRDRGAENAELNEYPWMV-----LLLYENRLSL-----IRYVLTAAHC--- 141

  Fly    88 NPTKQLYVAGG------------------ADSLNSRKQTRFFVVE---RRWHPQFRVLGG---ND 128
                   |.||                  .|.:.|..:.....||   ...|..|...||   ||
  Fly   142 -------VIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRND 199

  Fly   129 IAVLRIYPKFP-----------LDDVRFRSINFAGKPQRDSGTQASLVGWGRVGVGKIRKLQEMP 182
            ||:||:  :||           |.|..|        |.:|...|.|  ||     ...:..|.:.
  Fly   200 IALLRL--QFPVRYTKKIQPICLLDAEF--------PLQDLNLQIS--GW-----DPTKSSQTLI 247

  Fly   183 FLTM-ENDECQQSHRF-VFLKPLDICAMHLKGPR--GPCDGDSGAPLMNVAKEK------LYGLL 237
            ..|: |.:.....:|: .|.....:||   .|.|  ..|.|.||:|:|.:....      |.|:.
  Fly   248 TSTVKERNPADCLNRYPSFRSASQVCA---GGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIA 309

  Fly   238 SYGRKACTPLK-PYAFTRINAYSSWIQESM 266
            |||::.|.... |..:|:|..:|.||:.::
  Fly   310 SYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10041	NP_650177.2	Tryp_SPc	49..264	CDD:238113	68/269 (25%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	67/269 (25%)
		Tryp_SPc	108..335	CDD:214473	65/266 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7758
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950