DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10038 and Fam172a

DIOPT Version :9

Sequence 1:	NP_650176.3	Gene:	CG10038 / 41495	FlyBaseID:	FBgn0038013	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	XP_006517415.1	Gene:	Fam172a / 68675	MGIID:	1915925	Length:	418	Species:	Mus musculus

Alignment Length:	318	Identity:	110/318 - (34%)
Similarity:	152/318 - (47%)	Gaps:	64/318 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LKNFGYAFDGEGVLRKVDPATGEPGKELFSYNVSDDAAE-NEKHYQKLANQIPEIVYALLEKN-G 96
            |:.|.|||:.:|.||.:  .||||    |.:|..:|... |:|.|:.|...|...||.|||.: .
Mouse    81 LEGFEYAFNEKGQLRHI--KTGEP----FVFNYREDLHRWNQKRYEALGEIITRYVYELLESDCN 139

  Fly    97 LSRTYIPFD-QPPERSSFVFSQPAKLSQSKKLLVLIHGSGYVKAGQWARSLIINNSLDHGTQLPY 160
            |.:..||.| ...|..||:|.....|:..:||:|||||||.|:||||||.||||..||.|||:|:
Mouse   140 LKKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPF 204

  Fly   161 VRQAQKLGYDLLITNAN------------------DCT---------------------RFYNGK 186
            :::|...||.:::.|.|                  |.|                     .||...
Mouse   205 IKRAMDEGYGVIVLNPNENYIEVEKQKMHKQSSSSDGTDEPAGKRERRDKVSKETKKRRDFYEKY 269

  Fly   187 ENP----------IKGVNTSVEHVKYVWKNIVLPAKPESVAIVAHSYGGSLTLDL-VERFPDFFK 240
            .||          |:...:..||..|||.:.:..|..|:|..|||||||...::| ::|..| .|
Mouse   270 RNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREAD-VK 333

  Fly   241 ESVFAIAFTDAAMG---SPQAKN-KEYLCDVACDWVASNTPLDTPVSQSKSSIRRISA 294
            ..|.|:|.||:...   ....|. :|::.:..|:||:|:.||||.|........|:||
Mouse   334 SKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSA 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10038	NP_650176.3	None
Fam172a	XP_006517415.1	Arb2	<290..>339	CDD:370665	20/49 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850628
Domainoid	1	1.000	170	1.000	Domainoid score	I3751
eggNOG	1	0.900	-	-		E1_KOG3967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12933
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4108
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54552
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004036
OrthoInspector	1	1.000	-	-		oto91889
orthoMCL	1	0.900	-	-		OOG6_105983
Panther	1	1.100	-	-	LDO	PTHR21357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2870
SonicParanoid	1	1.000	-	-		X3883
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790