DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10013 and Ube2cbp

DIOPT Version :9

Sequence 1:	NP_650175.2	Gene:	CG10013 / 41494	FlyBaseID:	FBgn0038012	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_081670.1	Gene:	Ube2cbp / 70348	MGIID:	1917598	Length:	368	Species:	Mus musculus

Alignment Length:	221	Identity:	45/221 - (20%)
Similarity:	90/221 - (40%)	Gaps:	37/221 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 GLYLRRIRYSILDALTINVELGELPMCISPYNS-------CSLHCSNCTNEIIGQRQYYHIQEVP 149
            ||:||           :.|:....|..||.:|.       |:.:|.:|....|..|:...:..:|
Mouse    78 GLHLR-----------LRVQAESSPQPISVFNQSLQAQECCTFYCQSCGEVTIKDRKLLRVLPLP 131

  Fly   150 IT--TILPQNYFC---PRNRIPVYPSEEELYYGLNYLVVCSELLGNGVKTIAGRRRVLCSRCKKC 209
            ..  :.|...:.|   |....|::|.|.:.:.|.::.:|  .|..:..:......:|:|.|||..
Mouse   132 SENWSALVGEWCCHPDPFANRPLHPRENDCFIGDSFFLV--NLKSDLEQEPKANTKVICKRCKVT 194

  Fly   210 VGEFITRDVGVQLYADALRFVTLDSPLEFKE-IFGHVTPTQIMMRLVNDGEICGPDQRRLFLKAV 273
            :||.::        ::..:|...:..:...| .|.::..:|.:..::....:.....|..|...:
Mouse   195 LGETMS--------SETTKFYMTEVIIRPSEGSFPNIPRSQFLQSIIAQCLVELSSARSTFRFTI 251

  Fly   274 R-PDGQLQLL--HLEMDTKQMHILRS 296
            : .||::.:|  .|..|:..:..|||
Mouse   252 QGQDGKVYILLWVLNSDSLVIEPLRS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10013	NP_650175.2	HECT_2	<125..>256	CDD:303071	26/136 (19%)
Ube2cbp	NP_081670.1	HECT_2	13..358	CDD:286852	45/221 (20%)
		Interaction with UBE2C. /evidence=ECO:0000250	214..236		3/21 (14%)
		HECT-like. /evidence=ECO:0000250	332..368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4784
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900