Protein Alignment svp and Nr2c2

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_038964194.1
• Gene: Nr2c2 / 50659
• RGDID: 3201
• Length: 629
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 183/650 - (28%)
• Similarity: 262/650 - (40%)
• Gaps: 223/650 - (34%)

  Fly    61 PGTTTGSVATGGGGTTPS---SVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGG 122
            |.|.| |.....|.|:||   .:.|..|||     :.|...|..:....|.|..:.::: .|:|.
  Rat    22 PRTQT-SRPESPGMTSPSPRIQIISTDSAV-----ASPQRIQIVTDQQTGQKIQIVTAV-DASGS 79

  Fly   123 SAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQ--- 184
            |                              ..|.:|||..|  .|.|....:|...||..|
  Rat    80 S------------------------------KQQFILTSPDG--AGTGKVILASPETSSAKQLIF 112

  Fly   185 ---------------SSNSGSQIDSKQNIE-------CVVCGDKSSGKHYGQFTCEGCKSFFKRS 227
                           .|.|..::..|.:::       |||||||:||:|||..:|||||.|||||
  Rat   113 TTSDNLVPGRIQIVTDSASVERLLGKADVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRS 177

  Fly   228 VRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVP---------------- 276
            ||:|||||||.|::|.|::||||:||:|||||||:|||:.|:||..|.|
  Rat   178 VRKNLTYSCRSSQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTE 242

  Fly   277 ---------------PT---------QPGL--AGMHGQYQ------------------------- 290
                           ||         |.||  .||....|
  Rat   243 KIYIRKDLRSPLIATPTFVADKDGSRQTGLLDPGMLVNIQQPLIREDGTVLLATDSKAETSQGAL 307

  Fly   291 ----------------IANGDPM------------------------------------GIAGFN 303
                            :.|||..                                    ||....
  Rat   308 GTLANVVTSLANLSESLNNGDASEMQPEDQSASEITRAFDTLAKALNTTDSASPPSLADGIDASG 372

  Fly   304 GHSYLSSYISLLLRAEPYPTSRY-GQCMQPNNI-------------MGIDNICELAARLLFSAVE 354
            |.|     |.::.|.:..|.... |..:...::             :.:..|||.|:||||.::.
  Rat   373 GGS-----IHVISRDQSTPIIEVEGPLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMH 432

  Fly   355 WAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAA------GLHASPMAADR 413
            ||::||.|..|......:|:|..|:|||.|..:||:..:.::.:|||.      .:....::.||
  Rat   433 WARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDR 497

  Fly   414 VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYC 478
            :...|:||...||....:..|.:|..||:.|||||||:.|..||:..:.||..|||:|..|::|.
  Rat   498 IKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTGTSQIEKFQEKAQMELQDYV 562

  Fly   479 RTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYLPSM 543
            :..|.....|..::|:|||:||.:||.:.|:|||..|:|...|:::|            ||:..|
  Rat   563 QKTYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSII------------PYILKM 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	52/71 (73%)
		NR_LBD_COUP-TF	307..542	CDD:132746	79/254 (31%)
Nr2c2	XP_038964194.1	NR_DBD_TR2_like	145..231	CDD:143525	55/85 (65%)
		NR_LBD_TR2_like	394..615	CDD:132750	75/232 (32%)