Protein Alignment svp and rxrbb

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_571313.1
• Gene: rxrbb / 30486
• ZFINID: ZDB-GENE-990415-242
• Length: 422
• Species: Danio rerio
• Alignment Length: 459
• Identity: 167/459 - (36%)
• Similarity: 240/459 - (52%)
• Gaps: 81/459 - (17%)

  Fly   114 SSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPT-GCGSTTPSSQ 177
            :|||.:.  ||......|.....|.|:...||..:|              |.|: |.|..: :||
Zfish     2 NSLPPST--SAVSSPVSSVDSPLSAVSSSIGSPGVP--------------GTPSIGYGPIS-NSQ 49

  Fly   178 ANSSHSQS--------------------SNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKS 222
            .|||.|.|                    |.||..:..|:  .|.:|||:|||||||.::|||||.
Zfish    50 INSSMSVSRLHAVSSSDDVKPPFGLKSVSGSGPMLSQKR--MCAICGDRSSGKHYGVYSCEGCKG 112

  Fly   223 FFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHG 287
            ||||:||::|:|:||.::.|.:|:..||:|||||.:|||.|||:|||||..|....:     ..|
Zfish   113 FFKRTVRKDLSYTCRDNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQEERQKNKE-----RDG 172

  Fly   288 QYQIAN--GDPMGIAGFNGHSYLSSYISLLLRAE---PYPTSRYGQCM-QPNNIMGIDNICELAA 346
            .|:.::  .:.|.             :..:|.||   .:.|..:.... .||:  .:.|||:.|.
Zfish   173 DYECSSSANEEMP-------------VEKILEAETAVEHRTDLHSDATGSPND--PVTNICQAAD 222

  Fly   347 RLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAA 411
            :.||:.|||||.:|.|.::.:.|||.|||..|:||.:...|..|:.:. ..:|.|.|||....:.
Zfish   223 KQLFTLVEWAKRVPHFSDVPLDDQVILLRAGWNELLIAAFSHRSISVK-DEILLATGLHVPKEST 286

  Fly   412 DR--VVAFMDH------------IRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTH 462
            ..  |.||.|.            .|:..|.|.|::.:.:|..|..||:|||||..||.||:..:.
Zfish   287 HNLGVEAFFDRESSHSAEVGALFDRVLTELVCKMRDMQMDKTELGCLRAIVLFNPDAKGLTSSSE 351

  Fly   463 IESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRD 527
            :|.|:||...:||.||:.:||:|..||.|||||||:||::..:.:|.|||.:|:|.|||:|.:.:
Zfish   352 VELLREKVYASLESYCKQKYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGNTPIDTFLME 416

  Fly   528 MLLS 531
            ||.|
Zfish   417 MLES 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	45/71 (63%)
		NR_LBD_COUP-TF	307..542	CDD:132746	91/243 (37%)
rxrbb	NP_571313.1	Modulating. /evidence=ECO:0000250	1..89		26/105 (25%)
		Nuc_recep-AF1	<21..77	CDD:463363	16/70 (23%)
		NR_DBD_RXR	89..164	CDD:143514	46/74 (62%)
		Hinge. /evidence=ECO:0000250	156..178		8/26 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..182		4/25 (16%)
		NR_LBD_RXR_like	183..403	CDD:132741	83/235 (35%)