DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment svp and nr2f2

DIOPT Version :9

Sequence 1:	NP_001369011.1	Gene:	svp / 41491	FlyBaseID:	FBgn0003651	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_571258.1	Gene:	nr2f2 / 30424	ZFINID:	ZDB-GENE-990415-252	Length:	422	Species:	Danio rerio

Alignment Length:	384	Identity:	313/384 - (81%)
Similarity:	341/384 - (88%)	Gaps:	19/384 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 TSIKGQPTGCGST--TPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKS 222
            |.::|.|....:|  ||::|...|.|:.       ...|:|||||||||||||||||||||||||
Zfish    52 TPVQGPPNNNNNTQSTPTNQTTQSQSEK-------QQPQHIECVVCGDKSSGKHYGQFTCEGCKS 109

  Fly   223 FFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHG 287
            ||||||||||||:||.:|||||||||||||||||||||||:|||||||||||:|||||    .||
Zfish   110 FFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----HHG 170

  Fly   288 QYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQPNNIMGIDNICELAARLLFS 351
            |:.:.||||:     :.|||||.||||||||||||||||| |||||||||||:||||||||:|||
Zfish   171 QFALTNGDPL-----HCHSYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARMLFS 230

  Fly   352 AVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVA 416
            |||||:||||||:||:|||||||||.|||||||||:||||||||||||||||||||||:||||||
Zfish   231 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVA 295

  Fly   417 FMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQ 481
            |||||||||||||||||||||||||||||||||||:||||||||.|:||||||||||||||.|:|
Zfish   296 FMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQ 360

  Fly   482 YPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYL 540
            |||||||||||||||||||||||.|||||||||||||||||||||||||||:||:|||:
Zfish   361 YPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYM 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	67/71 (94%)
svp	NP_001369011.1	NR_LBD_COUP-TF	307..542	CDD:132746	216/235 (92%)
nr2f2	NP_571258.1	NR_DBD_COUP_TF	87..159	CDD:143516	67/71 (94%)
nr2f2	NP_571258.1	NR_LBD_COUP-TF	185..420	CDD:132746	216/235 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2291
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7628
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D296293at33208
OrthoFinder	1	1.000	-	-		FOG0001162
OrthoInspector	1	1.000	-	-		otm25721
orthoMCL	1	0.900	-	-		OOG6_106204
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3161
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.950