Protein Alignment svp and Rxrb

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_001192143.1
• Gene: Rxrb / 20182
• MGIID: 98215
• Length: 524
• Species: Mus musculus
• Alignment Length: 571
• Identity: 196/571 - (34%)
• Similarity: 275/571 - (48%)
• Gaps: 104/571 - (18%)

  Fly     6 STAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPP----HSAWHEPPASLGGHLHAASAG------ 60
            :|.|.|..||..:|   ....:|:.:.|..||..    ...|.:|.|:      ||:||
Mouse     4 ATRPPFLPPRHAAG---QCGPVGVRKEMHCGVASRWRRRRPWLDPAAA------AAAAGEQQALE 59

  Fly    61 --PGTTTGSVATGGGGTTPSSVASQQSAVIKQDL---SCPSLNQAGSGHHPGI-KEDLSSSLP-- 117
              || ..|....|..|....|..|.....:.|.:   |.|......|...|.: ...|.|..|
Mouse    60 PEPG-EAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVI 123

  Fly   118 SANGGSAG----GHHSGSGSGSGSGVN-----PGHGS----DMLPLIKGHGQDMLTSIKG----- 164
            |::.||.|    .....||..|...:|     ||.||    |:.|.:.|        ::|
Mouse   124 SSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLG--------VRGLHCPP 180

  Fly   165 QPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR 229
            .|.|.|                 :|.::       |.:|||:|||||||.::|||||.||||::|
Mouse   181 PPGGPG-----------------AGKRL-------CAICGDRSSGKHYGVYSCEGCKGFFKRTIR 221

  Fly   230 RNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANG 294
            ::||||||.:::|.:|:..||:|||||.:|||..||:|||||..|          ..|:.:..:|
Mouse   222 KDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEER----------QRGKDKDGDG 276

  Fly   295 DPMGIAGFNGHSYLSSYISLLLRAEPY-------PTSRYGQCMQPNNIMGIDNICELAARLLFSA 352
            |  |..|......:...:...|..|..       |.:..|....||:  .:.|||:.|.:.||:.
Mouse   277 D--GAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPND--PVTNICQAADKQLFTL 337

  Fly   353 VEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADR--VV 415
            |||||.||.|..|.:.|||.|||..|:||.:.:.|..|:.:... :|.|.|||....:|..  |.
Mouse   338 VEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDG-ILLATGLHVHRNSAHSAGVG 401

  Fly   416 AFMDH--IRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYC 478
            |..|.  .|:..|.|.|::.:.:|..|..||:||:||..||.|||:...:|.|:||...:||.||
Mouse   402 AIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYC 466

  Fly   479 RTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDML 529
            :.:||.|..||.|||||||:||::..:.:|.|||.:|:|.|||:|.:.:||
Mouse   467 KQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	45/71 (63%)
		NR_LBD_COUP-TF	307..542	CDD:132746	92/234 (39%)
Rxrb	NP_001192143.1	Modulating. /evidence=ECO:0000250	1..191		52/221 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..167		45/172 (26%)
		NR_DBD_RXR	191..266	CDD:143514	46/81 (57%)
		Hinge	258..382		43/138 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..285		7/33 (21%)
		NR_LBD_RXR_like	285..502	CDD:132741	84/219 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..323		4/24 (17%)