Protein Alignment svp and nhr-173

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_509119.4
• Gene: nhr-173 / 183862
• WormBaseID: WBGene00016975
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 102/454 - (22%)
• Similarity: 155/454 - (34%)
• Gaps: 126/454 - (27%)

  Fly   127 HHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSH--SQSSNSG 189
            |.|.|.|.|.|     .|||...::..........|.....|   ..|.::.:..|  ..:.|..
 Worm    23 HTSPSNSTSSS-----EGSDQQQIVSDFVDTASFMISWNGLG---EFPDTEEDIKHVIQPTENLS 79

  Fly   190 SQIDSKQNIE-------------CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRN 241
            ..|:.::.|.             |.||||:::|.||...:|.|||:||:|:|.....|.|.....
 Worm    80 LNIEEQKEIVAFHHLPRNVCPTICAVCGDRATGYHYEVPSCNGCKTFFRRTVLSQRKYECMRGGK 144

  Fly   242 C--PIDQHHRNQCQYCRLKKCLKMGMRREAVQR----------------------GRVPPTQ--- 279
            |  .:.:..|..|:.||.:||:::||...|:|.                      ..:|.|.
 Worm   145 CFNVLPKEKRCSCRSCRFQKCVEVGMNPFAIQTNDSLSSNAVVTKIVGKRKNSVDNSIPSTSKLT 209

  Fly   280 --PGLAGMHG---------QYQIANGDPMGIAGFN--GHSYLS--------SYISLLLRAEPYPT 323
              |.:..|..         .|.....|......:|  .|.|.|        ..||:..:..|.|.
 Worm   210 VLPEVISMDNAIDRLIDGLMYLEIKVDDFRSCAYNPPTHEYRSLKYHLEQQPMISMADKLGPMPN 274

  Fly   324 ----------------SRYGQCMQP--NNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQ 370
                            |...:.|.|  .|....|         :.::||:||...|..::...||
 Worm   275 WPLRQISHEEMKEYIESGNSEPMTPERKNWFVYD---------ILTSVEYAKTFMFLHQIGKEDQ 330

  Fly   371 VALLRLVWSELFVLN------ASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVE 429
            :.|||.|..:|..||      .::..|..|....:.......:....|.:...|.     ::::|
 Worm   331 ILLLRAVVLKLMHLNQAFYSYENKYDMIFHPDGTVPPHSWKKNENPNDSISQMMT-----KQKME 390

  Fly   430 KLK-----------ALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESL----QEKSQCALEEYC 478
            ::|           ...:|..||...|||.|......||||  |...:    :||...||.:||
 Worm   391 EMKEEFTLSIRQFVTYQLDKREYVLFKAITLCNATISGLSD--HAREVVTREKEKYSKALMKYC 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	28/73 (38%)
		NR_LBD_COUP-TF	307..542	CDD:132746	49/219 (22%)
nhr-173	NP_509119.4	NR_DBD_HNF4A	103..180	CDD:143518	29/76 (38%)
		HOLI	307..476	CDD:214658	39/162 (24%)