Protein Alignment svp and nhr-129

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_001122887.1
• Gene: nhr-129 / 183635
• WormBaseID: WBGene00003719
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 432
• Identity: 102/432 - (23%)
• Similarity: 165/432 - (38%)
• Gaps: 111/432 - (25%)

  Fly   184 QSSNSGSQIDSKQNI-----------ECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCR 237
            :.|.|.|.:|..:.|           :|.|||..:||.||....|.|||:||:|.|.....::|:
 Worm     3 EPSCSNSPVDLPEIIPQLKVYAERPKDCFVCGGSASGYHYDVPACNGCKTFFRRYVISKRLFTCK 67

  Fly   238 GSRNCPIDQHHRN---QCQYCRLKKCLKMGM--------------------RREAVQRGRVPPTQ 279
            .:.:| .|...|:   :|:.||:.||..:||                    |:..:....|...|
 Worm    68 LNDDC-FDLSTRDVPVKCRACRINKCFAVGMNPHALEVDKTNTDCLKEVTKRKNMIGNDAVNEKQ 131

  Fly   280 ---PGLAGMHGQYQ-IANG--------DPMGIAGFNGH-------SYL---SSYISLLLRAEPYP 322
               ..|..|..:.| ||:.        |....:.:|.|       .::   ::.|||..:..|.|
 Worm   132 LVLNSLESMENKIQKIADMLTYLELKLDQFRASSYNPHWAEVRGLEFVLNSTNRISLADKFGPMP 196

  Fly   323 TSRYGQCMQPNN---------------IMGIDNICELAARLLF----SAVEWAKNIPFFPELQVT 368
                |..:..||               |.|...........|:    :.:|:||...||.||...
 Worm   197 ----GWPLLDNNLSPSRPPPLSHEKLVIGGPPPYSPKKKHWLYFNMLATIEYAKTFMFFHELLPR 257

  Fly   369 DQVALLRLVWSELFVLN--------ASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQ 425
            ||:.|:|  ::.|..:|        :.:....:|....|.   :|.:.......|  |..|.:.:
 Worm   258 DQLILIR--YTTLACVNLLVSFSSVSKKYDTAVHPDGTLQ---MHRNQEYYSSNV--MSIIPLIR 315

  Fly   426 EQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESL----QEKSQCALEEYCRTQYPNQP 486
            .||:::        ||..||||.|.......||  .|.:.|    ::|...||.::|.....|.|
 Worm   316 YQVQQI--------EYVLLKAICLCNPAVPDLS--KHAQLLLAEERQKYSEALLDHCIRNIGNGP 370

  Fly   487 TRFGKLLLRLPSLRTVS--SQVIEQLFFVRLVGKTPIETLIR 526
            :||..|:..:..|....  .:.:..|:...||.|||.:.:::
 Worm   371 SRFTDLIGIIDVLERQQRMQKDLHLLYIAPLVAKTPKDNIVQ 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	28/94 (30%)
		NR_LBD_COUP-TF	307..542	CDD:132746	59/256 (23%)
nhr-129	NP_001122887.1	ZnF_C4	30..99	CDD:197701	27/69 (39%)
		HOLI	236..386	CDD:214658	42/166 (25%)