Protein Alignment svp and nhr-120

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_509116.2
• Gene: nhr-120 / 182882
• WormBaseID: WBGene00003710
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 111/533 - (20%)
• Similarity: 186/533 - (34%)
• Gaps: 159/533 - (29%)

  Fly    90 QDLSCPSLNQAGSGHHPG----IKEDLSSSLPSAN--GGSAGGHHSGSGSGSGSGVNPGHGSDML 148
            :.::|..|:::....||.    |..|      |.|  .||...|...|             ||.:
 Worm     6 ETMNCTHLDKSNKLLHPSPPMWINRD------SMNWVDGSLSSHSPMS-------------SDSI 51

  Fly   149 PLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNI------ECVVCGDKS 207
            ..::...:|               |...:.:|:..|..   :.|...:|:      .|.||||:.
 Worm    52 SPLRSPAED---------------TNMVECSSNELQPP---APIRKIRNVRKSDKHHCSVCGDRP 98

  Fly   208 SGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQR 272
            :|.||...:|.|||:||:|::..:..:.|....||...:..|..|:.||.:||:::||...|:|
 Worm    99 TGYHYDVLSCNGCKTFFRRTIINSRNFICTKGGNCQFTKDFRCACRACRFEKCVRVGMNPSAIQ- 162

  Fly   273 GRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRY----------- 326
                  .|.....:....:.:||.......:....|..::|..||.....|.|:
 Worm   163 ------FPSSKNHNEADDMDSGDEDSNIQDDKSLALIPFVSAPLRETTIHTYRWVDDIFRREDAV 221

  Fly   327 -----------------GQCMQPNNIMGIDNICELAARLLFS--------------AVEWAKNIP 360
                             |:.::.|.::|.|...:.....|::              .||:||...
 Worm   222 LRHRIPGTLPVEDDFCLGELLRKNILIGGDCAIDRKPGTLYTNDPVRYWMVVDLLLIVEFAKTFE 286

  Fly   361 FFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQ 425
            .|.:|...||..|:            |.....|||    |....::...|....:.|.|.|..|:
 Worm   287 SFRKLSEFDQKCLI------------SHIGGVLHV----ATQSFYSYFEAKSSTLTFPDGINAFE 335

  Fly   426 EQ---VEK-------------------------LKALHVDSAEYSCLKAIVLFTTDACGLSDVTH 462
            .:   |||                         ||. .|...|||..|:|.||:.|...:||...
 Worm   336 RKMADVEKDDKRRSRKVFLNYYAEMYNAPVNEFLKN-KVTMTEYSFFKSISLFSPDNLEMSDAGR 399

  Fly   463 IESLQEKSQCA--LEEYCRTQYPNQ--PTRFGKLLLRLPSLRTVSSQVIEQLFFVRL-------V 516
            :.:.:|:.:..  |.:|...:|..:  ..||..:|:.:.:......:..:.:..:.|       :
 Worm   400 LIANEERERLTTLLRKYLVAEYGFKVGMNRFSLILMAISTFVNYGEKRRDYISLMSLLKFDLANI 464

  Fly   517 GK-----TPIETL 524
            ||     .|||.|
 Worm   465 GKDIYLRKPIEML 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	27/71 (38%)
		NR_LBD_COUP-TF	307..542	CDD:132746	60/304 (20%)
nhr-120	NP_509116.2	NR_DBD_HNF4A	91..164	CDD:143518	28/79 (35%)
		NR_LBD	267..440	CDD:132726	42/189 (22%)