Protein Alignment svp and nhr-154

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_506037.2
• Gene: nhr-154 / 182565
• WormBaseID: WBGene00007547
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 418
• Identity: 90/418 - (21%)
• Similarity: 159/418 - (38%)
• Gaps: 90/418 - (21%)

  Fly   174 PSSQANSSHSQSSNSGSQIDS--------------KQNIECVVCGDKSSGKHYGQFTCEGCKSFF 224
            |..:...:.::.|.|...|.|              |...:|:||.:.:.|.||...:|.|||:||
 Worm    43 PDQEVFQNQNEFSASPPDISSPFADEKIYKSLPRNKCPSKCLVCRNPAIGYHYDVPSCNGCKTFF 107

  Fly   225 KRSVRRNLTYSCRGSRNC-----PIDQHHRNQCQYCRLKKCLKMGMRREAVQ------RGRVPPT 278
            :|::.....::|...:.|     |:|...| .|:.||..||:::||...|:|      .|:|..:
 Worm   108 RRTIITGRKFTCAKQKKCMDGTEPVDMSKR-LCRACRFAKCVEVGMNPMAIQAEVKTDEGKVLRS 171

  Fly   279 QPGLAGMHGQYQIANGDPMGIAG---FNGHSYLSSYISLL--LRAEPYPTSRYGQCMQPNNIMGI 338
            :          .:...:.:|:..   ......||..|..|  :.::..|..|.|......:|..:
 Worm   172 E----------VLNQRESLGVVSSLIVTEEDLLSRMIEKLTFVESKVEPLHRSGMPPGYRDIRKL 226

  Fly   339 DNICELAARLL--------------------------------FSAVEWAKNIPFFPELQVTDQV 371
            :.|.:....|:                                .:::|.:|...|..:|.:..::
 Worm   227 EEILDSKPVLVVTDIPNLKFCPSPCANEKRPRRHFTNYVHTSYLASLESSKMFEFSSQLDLESRI 291

  Fly   372 ALLR---LVWSEL----FVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVE 429
            .|::   |:.|.:    |.:|..:..:..|  |..:.:| |......:..| ..||:::.|:.:.
 Worm   292 LLMKHATLICSNMMNAFFSINEMKSDILRH--PDGSMSG-HMRKFDRENDV-MTDHVKLIQKTLI 352

  Fly   430 KLKALHVDSAEYSCLKAIVLFTTDACGLSDVTH--IESLQEKSQCALEEYCRTQYP--NQPTRFG 490
            ......||..||...|||:|......||.....  ||..:.:...||..||..|:.  ..||||.
 Worm   353 TFLNHKVDKIEYLLFKAIMLCNPAVPGLDSWNQEIIEKERNQYVKALLNYCLLQHGKLQGPTRFA 417

  Fly   491 KLLLRLPSLRTVSSQVIEQLFFVRLVGK 518
            .:|...|.:...|..  ::.|.|.:..|
 Worm   418 TILAMAPIIENQSKN--QKDFHVYIKAK 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	27/82 (33%)
		NR_LBD_COUP-TF	307..542	CDD:132746	54/257 (21%)
nhr-154	NP_506037.2	NR_DBD_HNF4A	83..160	CDD:143518	27/77 (35%)
		HOLI	266..429	CDD:214658	40/166 (24%)