Protein Alignment svp and Nr2f2

DIOPT Version :9

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_033827.2
• Gene: Nr2f2 / 11819
• MGIID: 1352452
• Length: 414
• Species: Mus musculus
• Alignment Length: 436
• Identity: 323/436 - (74%)
• Similarity: 349/436 - (80%)
• Gaps: 41/436 - (9%)

  Fly   106 PGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCG 170
            ||.:...:|..|...|...|..|:....|.|     |..|.......| ||       |.|.|.|
Mouse    16 PGSQGSQASQAPPVPGPPPGAPHTPQTPGQG-----GPASTPAQTAAG-GQ-------GGPGGPG 67

  Fly   171 STTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYS 235
            |.....|                  |:|||||||||||||||||||||||||||||||||||:|:
Mouse    68 SDKQQQQ------------------QHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYT 114

  Fly   236 CRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIA 300
            ||.:|||||||||||||||||||||||:|||||||||||:|||||    .|||:.:.||||:
Mouse   115 CRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----THGQFALTNGDPL--- 172

  Fly   301 GFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPE 364
              |.|||||.|||||||||||||||:| |||||||||||:||||||||:||||||||:||||||:
Mouse   173 --NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPD 235

  Fly   365 LQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVE 429
            ||:|||||||||.|||||||||:||||||||||||||||||||||:|||||||||||||||||||
Mouse   236 LQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVE 300

  Fly   430 KLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLL 494
            ||||||||||||||||||||||:||||||||.|:||||||||||||||.|:||||||||||||||
Mouse   301 KLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLL 365

  Fly   495 RLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYL 540
            ||||||||||.|||||||||||||||||||||||||||:||:|||:
Mouse   366 RLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYM 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	66/71 (93%)
		NR_LBD_COUP-TF	307..542	CDD:132746	215/235 (91%)
Nr2f2	NP_033827.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..72		19/68 (28%)
		NR_DBD_COUP_TF	79..151	CDD:143516	66/71 (93%)
		Interaction with ZFPM2. /evidence=ECO:0000269|PubMed:11382775	117..414		264/304 (87%)
		NR_LBD_COUP-TF	177..411	CDD:132746	214/233 (92%)
		Important for dimerization	337..414		69/75 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2346
eggNOG	1	0.900	-	-		E33208_3BBKC
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7628
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3459
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001162
OrthoInspector	1	1.000	-	-		otm43398
orthoMCL	1	0.900	-	-		OOG6_106204
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3161
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.750