Protein Alignment svp and Nr2f2

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_542956.1
• Gene: Nr2f2 / 113984
• RGDID: 69305
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 437
• Identity: 319/437 - (72%)
• Similarity: 350/437 - (80%)
• Gaps: 43/437 - (9%)

  Fly   106 PGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCG 170
            ||.:...:|..|...|...|..|:..        .||.|..
  Rat    16 PGSQGSQASQAPPVPGPPPGAPHTPQ--------TPGQGGP------------------------ 48

  Fly   171 STTPSSQANSSHSQSSNSGS-QIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY 234
            ::||:..|..|.......|| :...:|:|||||||||||||||||||||||||||||||||||:|
  Rat    49 ASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSY 113

  Fly   235 SCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGI 299
            :||.:|||||||||||||||||||||||:|||||||||||:|||||    .|||:.:.||||:
  Rat   114 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----THGQFALTNGDPL-- 172

  Fly   300 AGFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFP 363
               |.|||||.|||||||||||||||:| |||||||||||:||||||||:||||||||:||||||
  Rat   173 ---NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFP 234

  Fly   364 ELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQV 428
            :||:|||||||||.|||||||||:||||||||||||||||||||||:||||||||||||||||||
  Rat   235 DLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQV 299

  Fly   429 EKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLL 493
            |||||||||||||||||||||||:||||||||.|:||||||||||||||.|:|||||||||||||
  Rat   300 EKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL 364

  Fly   494 LRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYL 540
            |||||||||||.|||||||||||||||||||||||||||:||:|||:
  Rat   365 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYM 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	66/71 (93%)
		NR_LBD_COUP-TF	307..542	CDD:132746	215/235 (91%)
Nr2f2	NP_542956.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..72		16/87 (18%)
		NR_DBD_COUP_TF	79..151	CDD:143516	66/71 (93%)
		Interaction with ZFPM2. /evidence=ECO:0000250	117..414		264/304 (87%)
		NR_LBD_COUP-TF	177..411	CDD:132746	214/233 (92%)
		Important for dimerization	337..414		69/75 (92%)