DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment svp and nr2f5

DIOPT Version :9

Sequence 1:	NP_001369011.1	Gene:	svp / 41491	FlyBaseID:	FBgn0003651	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	XP_002938509.1	Gene:	nr2f5 / 100491959	XenbaseID:	XB-GENE-486334	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	407	Identity:	299/407 - (73%)
Similarity:	339/407 - (83%)	Gaps:	19/407 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 VNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSS-NSGSQIDSKQNIECVV 202
            |||  ..:.:|.:.|...:....:..|..|....||::.......|.. :||.:  ...|::|:|
Frog     5 VNP--WQEDIPGVPGSQVNNPPGLCNQDPGGTPQTPTTPKGGVPGQDPVHSGDK--GVPNVDCLV 65

  Fly   203 CGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRR 267
            ||||||||||||||||||||||||||||||||:|||:|:|||||||||||||||||||||:||||
Frog    66 CGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRGNRDCPIDQHHRNQCQYCRLKKCLKVGMRR 130

  Fly   268 EAVQRGRV--PPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG-QC 329
            |||||||:  |.|.|      |||.:.|.||     :||||||:.:|||||||||||||||| ||
Frog   131 EAVQRGRMSHPQTSP------GQYTLNNVDP-----YNGHSYLTGFISLLLRAEPYPTSRYGAQC 184

  Fly   330 MQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLH 394
            :||||||||:|||||||||||||:||||||||||:.|::|||:|||:.|||||||||:|||||||
Frog   185 LQPNNIMGIENICELAARLLFSAIEWAKNIPFFPDFQLSDQVSLLRMTWSELFVLNAAQCSMPLH 249

  Fly   395 VAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSD 459
            |||||||||||||||:||||||||||||:||||||||||||||||||||||||.|||.||.||||
Frog   250 VAPLLAAAGLHASPMSADRVVAFMDHIRVFQEQVEKLKALHVDSAEYSCLKAIALFTPDAVGLSD 314

  Fly   460 VTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETL 524
            :.|:||:|||||||||||.|.||||||||||:|||||||||.||:.|||||||||||||||||||
Frog   315 IGHVESIQEKSQCALEEYVRNQYPNQPTRFGRLLLRLPSLRIVSAPVIEQLFFVRLVGKTPIETL 379

  Fly   525 IRDMLLSGNSFSWPYLP 541
            ||||||||:||:|||:|
Frog   380 IRDMLLSGSSFNWPYMP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	66/71 (93%)
svp	NP_001369011.1	NR_LBD_COUP-TF	307..542	CDD:132746	203/236 (86%)
nr2f5	XP_002938509.1	NR_DBD_COUP_TF	63..135	CDD:143516	66/71 (93%)
nr2f5	XP_002938509.1	NR_LBD_COUP-TF	161..397	CDD:132746	203/236 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D296293at33208
OrthoFinder	1	1.000	-	-		FOG0001162
OrthoInspector	1	1.000	-	-		otm48542
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.020