Protein Alignment svp and foxn1

DIOPT Version :10

• Sequence 1: NP_001369011.1
• Gene: svp / 41491
• FlyBaseID: FBgn0003651
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_017947285.2
• Gene: foxn1 / 100485276
• XenbaseID: XB-GENE-954872
• Length: 663
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 109/663 - (16%)
• Similarity: 195/663 - (29%)
• Gaps: 231/663 - (34%)

  Fly   154 HGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSS--NSGSQIDSKQNIECVVCGDKSSGKH---YG 213
            |.|::|          .||....|:|.:.|..|  |..|.|:...:......|..||..|   ||
 Frog    24 HNQELL----------ASTIMQDQSNLTFSSGSLDNECSPINQTDDGILEQAGSSSSCLHMDTYG 78

  Fly   214 QFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPT 278
            ..|.:      .:..|:|...|...|.:.|.:|              ::||.           |:
 Frog    79 SHTID------IQGERKNSDSSVSPSLSSPQEQ--------------IQMGF-----------PS 112

  Fly   279 QPGLAGMHGQYQIANGDPMGIAGF-----NGHSYLSSYI--------SLLLRAEPYPTSRYGQCM 330
            :.....:..:|...:....|.:.|     ..|.|...:.        ||.|..:.:        .
 Frog   113 KSSPREVFRRYSCDDTTERGYSNFIKDRNQFHPYKRQFSDVFPNTLDSLSLAEKTF--------K 169

  Fly   331 QPNNIMGIDNIC----------------ELAAR------LLFSAVEWAKNIPFFPELQVTDQVAL 373
            :.|.|...:::|                :::|.      :.:::.:....|....|:::...|..
 Frog   170 EMNRIDTFEDVCPPPGPEHIEPFVPHVPDISAEQAWCNSVQYNSTDEDSQIMLGSEVKMKSSVMC 234

  Fly   374 -----LRLVWSELFVLNASQCSMPLH--------------------VAP---LLAAAGLHASPMA 410
                 .|:.||:...:..:..|.|.:                    :||   :.|...|:..|:.
 Frog   235 QQEKEQRMYWSQTQQIYCTPQSFPQYSTGGSYPVTYISTSHYPYQRIAPQASMEAQQPLYPKPIY 299

  Fly   411 ADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACG-LSDVTH-------IESLQ 467
            :..::.||      ..:..|..:|.|........:....|.|...| .:.|.|       .|.::
 Frog   300 SYSILIFM------ALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVE 358

  Fly   468 EKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLR-----TVSSQVIEQLFFVRLVGKTPIETLIRD 527
            .||..:..:.|  .:...|.:..|:...|...:     ||...:.:.....:|:|:...:  :|.
 Frog   359 NKSGSSSRKGC--LWALNPAKIDKMQEELQKWKRKDPVTVRKSMAKPEDLDKLIGERTEK--LRS 419

  Fly   528 MLLSGNSFSWPYLPSMXHTMWR-QLTTTXSSAAAVAAATLNINSGGGGIGIGGGGSGSGGGGSGG 591
            .||:.::......|:|..:|.: .|..|..|...|:..:::
 Frog   420 SLLAHSAAGLVNSPTMQLSMQQTPLCETTISPVPVSLQSMH------------------------ 460

  Fly   592 GGGVVGCGSHNVVAASHDQ------------LANVAVMQQTYGSGGSSSSSISGCHNGNNGSGGS 644
               .:....||....|..|            ..:.|::||.:|.
 Frog   461 ---DISASLHNNTHLSRQQPPRYTPLPHDIPQISPAMIQQPHGI--------------------- 501

  Fly   645 ICNQQINNYGNNSNNNVGNHMSAGSFFGGSNNSIHSSGNSNTDYMTTPATAYATPATAATSTVNT 709
                                         |.|...|..|.| |....|.....:|..|.|..:.|
 Frog   502 -----------------------------SQNHFSSPDNQN-DLRAQPINPQDSPIPAHTPPLQT 536

  Fly   710 TTMLSNYCDAATM 722
            ..|||.:..|.||
 Frog   537 MKMLSEHSPARTM 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	15/74 (20%)
		NR_LBD_COUP-TF	307..542	CDD:132746	45/305 (15%)
foxn1	XP_017947285.2	COG5025	<288..540	CDD:227358	53/339 (16%)
		FH_FOXN1	295..391	CDD:410830	18/103 (17%)