DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment svp and nr2f1

DIOPT Version :9

Sequence 1:	NP_001369011.1	Gene:	svp / 41491	FlyBaseID:	FBgn0003651	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	XP_012815199.1	Gene:	nr2f1 / 100101681	XenbaseID:	XB-GENE-480018	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	410	Identity:	321/410 - (78%)
Similarity:	344/410 - (83%)	Gaps:	22/410 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 GSGSGVNPG-HGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQN 197
            |:..|.||| ......|....| .....|..|.|:..|:.....|..|..||          :|:
Frog    18 GNPGGPNPGAREQQQAPSAAPH-TPQTPSQPGPPSTPGAAGDKGQQGSGQSQ----------QQH 71

  Fly   198 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLK 262
            |||||||||||||||||||||||||||||||||||||:||.:|||||||||||||||||||||||
Frog    72 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLK 136

  Fly   263 MGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG 327
            :|||||||||||:|||||.    .|||.:.||||:     |||.|||.|||||||||||||||||
Frog   137 VGMRREAVQRGRMPPTQPN----PGQYALTNGDPL-----NGHCYLSGYISLLLRAEPYPTSRYG 192

  Fly   328 -QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSM 391
             |||||||||||:|||||||||||||||||:||||||:||:|||||||||.|||||||||:||||
Frog   193 SQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSM 257

  Fly   392 PLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACG 456
            ||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||:||||
Frog   258 PLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 322

  Fly   457 LSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPI 521
            |||..||||||||||||||||.|:||||||:|||||||||||||||||.||||||||||||||||
Frog   323 LSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPI 387

  Fly   522 ETLIRDMLLSGNSFSWPYLP 541
            |||||||||||:||:|||:|
Frog   388 ETLIRDMLLSGSSFNWPYMP 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	67/71 (94%)
svp	NP_001369011.1	NR_LBD_COUP-TF	307..542	CDD:132746	217/236 (92%)
nr2f1	XP_012815199.1	NR_DBD_COUP_TF	74..146	CDD:143516	67/71 (94%)
nr2f1	XP_012815199.1	NR_LBD_COUP-TF	172..407	CDD:132746	216/234 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D296293at33208
OrthoFinder	1	1.000	-	-		FOG0001162
OrthoInspector	1	1.000	-	-		otm48542
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3161
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040