DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment svp and nr2f2

DIOPT Version :9

Sequence 1:	NP_001369011.1	Gene:	svp / 41491	FlyBaseID:	FBgn0003651	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	XP_012813815.1	Gene:	nr2f2 / 100038039	XenbaseID:	XB-GENE-482566	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	321/408 - (78%)
Similarity:	348/408 - (85%)	Gaps:	28/408 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 PGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGD 205
            ||.|.        :|........||  |..|||| :|:|.|...|.|.|.:...:|:||||||||
Frog    25 PGQGP--------NGAPHTPQTPGQ--GVPSTTP-AQSNPSSQPSQNQGEKQQQQQHIECVVCGD 78

  Fly   206 KSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRRE-- 268
            |||||||||||||||||||||||||||||:||.:|||||||||||||||||||||||:|||||
Frog    79 KSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREVS 143

  Fly   269 -----AVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG- 327
                 ||||||:|||||    .|||:.:.||||:     |.|||||.|||||||||||||||:|
Frog   144 SLFTAAVQRGRMPPTQP----THGQFALTNGDPL-----NCHSYLSGYISLLLRAEPYPTSRFGS 199

  Fly   328 QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMP 392
            |||||||||||:||||||||:||||||||:||||||:||:|||||||||.|||||||||:|||||
Frog   200 QCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMP 264

  Fly   393 LHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGL 457
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||:|||||
Frog   265 LHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGL 329

  Fly   458 SDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIE 522
            |||.|:||||||||||||||.|:||||||||||||||||||||||||.|||||||||||||||||
Frog   330 SDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 394

  Fly   523 TLIRDMLLSGNSFSWPYL 540
            ||||||||||:||:|||:
Frog   395 TLIRDMLLSGSSFNWPYM 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svp	NP_001369011.1	NR_DBD_COUP_TF	200..272	CDD:143516	67/78 (86%)
svp	NP_001369011.1	NR_LBD_COUP-TF	307..542	CDD:132746	215/235 (91%)
nr2f2	XP_012813815.1	NR_DBD_COUP_TF	73..143	CDD:143516	65/69 (94%)
nr2f2	XP_012813815.1	NR_LBD_COUP-TF	178..413	CDD:132746	215/235 (91%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7628
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D296293at33208
OrthoFinder	1	1.000	-	-		FOG0001162
OrthoInspector	1	1.000	-	-		otm48542
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3161
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.050