DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MAX and Max

DIOPT Version :9

Sequence 1:	NP_002373.3	Gene:	MAX / 4149	HGNCID:	6913	Length:	160	Species:	Homo sapiens
Sequence 2:	NP_001246833.1	Gene:	Max / 40095	FlyBaseID:	FBgn0017578	Length:	161	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	73/177 - (41%)
Similarity:	108/177 - (61%)	Gaps:	41/177 - (23%)

- Green bases have known domain annotations that are detailed below.

Human     1 MSDND-DIEVESDEE--------------QPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSV 50
            |||:| ||::||||:              ...| :.|:||||||||||:||||||:||.:||::|
  Fly     3 MSDDDRDIDIESDEDGDSDTGLGSSRHTNTANF-TQAEKRAHHNALERRRRDHIKESFTNLREAV 66

Human    51 PSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNY 115
            |:|:||||||||||.|.||.||.||||...:|:||:::||||.::.:|::|||
  Fly    67 PTLKGEKASRAQILKKTTECIQTMRRKISENQKDIEEIKRQNNIIAKQIQALE------------ 119

Human   116 PSSDNSLYTNAKGSTISAF----DGGSDSSSESEPEEPQSRKKLRME 158
                     ::.|...|.|    :.||:.:.:.:.::..||:..:|:
  Fly   120 ---------SSNGDQFSEFLSDEEVGSEEADDEDLDQDFSRRNKKMK 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAX	NP_002373.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40		26/53 (49%)
		bHLHzip_Max	24..92	CDD:381412	47/67 (70%)
		Leucine-zipper	81..102		8/20 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	103..160		9/60 (15%)
		Nuclear localization signal	152..156		1/3 (33%)
Max	NP_001246833.1	HLH	40..91	CDD:278439	38/50 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148044
Domainoid	1	1.000	81	1.000	Domainoid score	I8588
eggNOG	1	0.900	-	-		E1_KOG2483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4778
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545748at2759
OrthoFinder	1	1.000	-	-		FOG0005533
OrthoInspector	1	1.000	-	-		oto88407
orthoMCL	1	0.900	-	-		OOG6_104805
Panther	1	1.100	-	-	LDO	PTHR10328
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4638
SonicParanoid	1	1.000	-	-		X5516
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790