DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3942 and PGC1

DIOPT Version :9

Sequence 1:	NP_650171.2	Gene:	CG3942 / 41489	FlyBaseID:	FBgn0038008	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_015118.1	Gene:	PGC1 / 855895	SGDID:	S000006127	Length:	321	Species:	Saccharomyces cerevisiae

Alignment Length:	388	Identity:	76/388 - (19%)
Similarity:	143/388 - (36%)	Gaps:	119/388 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 IGHKGSGNTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQLTQDAQVVVYHDFVLRFMLQRMPS 434
            :||:.....|       .||||..|::|..|.||::|.|:|:|.|..|||.||           |
Yeast     5 VGHRAFKARY-------PENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHD-----------S 51

  Fly   435 FEDLLENQDLLI--FAYENLNKLMLLAMGGSKRKDLIAVPLEAFSYDQLKEVKVLRFAGSKGCDK 497
            ....:.:::|:|  ..:|.:.:|.....|......|..:...|..:...|.:..::|...|
Yeast    52 DTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEK---- 112

  Fly   498 SCDRMLLEQRPFPLLLDLLDEENLPVDMGFLIEIKWPQMTNMRRW---------ESGSFKPTFDR 553
                 ::..:.|.::|::.:      |:.|     |.:......|         |:|..|
Yeast   113 -----IIMIKTFVIMLEVKN------DLKF-----WQERITWGLWLLDWYDFGIETGVLK----- 156

  Fly   554 NFYVDTILEIVLNKAGKRRIVFCSFDADICAMVRFKQNVYPVTLLLEDPHSPVQYADQRVSVQDV 618
            :|                :::..|...||.:  :|.:.    :|.|.|||         ..:..:
Yeast   157 DF----------------KVIVISLSLDIAS--QFVKR----SLTLNDPH---------YKLFGI 190

  Fly   619 AVRFCNS------LEFLGLTLHANSL------LNKPSTMAYLHQINLDAFVYGSSTID-LEIRNK 670
            :|.|.:|      |..|.: |..|.:      :|||....||.::.    ::|:.|.| ::.|..
Yeast   191 SVHFVSSWTSQFRLRLLPV-LMKNDIKVYLWTVNKPIDFKYLCELP----IHGAITDDPIKARKL 250

  Fly   671 LKKHGVLGIIYDRLDQLDQVGEELEGDTMCTIDSVTTRRVIQETEV------EEW--IQKCGY 725
            ...|.|.        :.....::....::.::|.:.....|:...:      .:|  |:.||:
Yeast   251 CDGHTVA--------KKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGW 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888
		GDPD_GDE5	368..684	CDD:176549	70/337 (21%)
		GDPD	372..685	CDD:281062	69/336 (21%)
PGC1	NP_015118.1	GDPD_YPL206cp_fungi	4..244	CDD:176512	66/317 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900