DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3942 and GDPD5

DIOPT Version :9

Sequence 1:	NP_650171.2	Gene:	CG3942 / 41489	FlyBaseID:	FBgn0038008	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	XP_011543578.1	Gene:	GDPD5 / 81544	HGNCID:	28804	Length:	606	Species:	Homo sapiens

Alignment Length:	173	Identity:	34/173 - (19%)
Similarity:	58/173 - (33%)	Gaps:	67/173 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 IGHKGSGNTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQLTQDAQVVVYHDFVLR-------- 426
            |||:|:       ..:..|:||..|::|:......::.|:.::.|....:.||..||
Human   231 IGHRGA-------PMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEE 288

  Fly   427 --------------FMLQRM-------------------PSFEDLLENQDLLIFAYENLNKLMLL 458
                          ..|||:                   ||.....:||.:.     :|.:|:.|
Human   289 FPELARRPASMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSIC-----SLAELLEL 348

  Fly   459 AMGGSK--------------RKDLIAVPLEAFSYDQLKEVKVL 487
            |.|.:.              |...|.|.|||..:....:.:|:
Human   349 AKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQHQVM 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888
		GDPD_GDE5	368..684	CDD:176549	34/173 (20%)
		GDPD	372..685	CDD:281062	32/171 (19%)
GDPD5	XP_011543578.1	GDPD_GDE2	227..577	CDD:176550	34/173 (20%)
GDPD5	XP_011543578.1	UgpQ	227..468	CDD:223657	34/173 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900