DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3942 and GDPD3

DIOPT Version :9

Sequence 1:	NP_650171.2	Gene:	CG3942 / 41489	FlyBaseID:	FBgn0038008	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_077283.2	Gene:	GDPD3 / 79153	HGNCID:	28638	Length:	318	Species:	Homo sapiens

Alignment Length:	164	Identity:	38/164 - (23%)
Similarity:	66/164 - (40%)	Gaps:	62/164 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 PNFRCDLSHSYERYWRKNRLCMNIGHKGSGNTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQL 411
            |.||..|.                .|:|       ||..:.|||:...:.::...:|::|:|.||
Human    35 PTFRIRLG----------------AHRG-------GSGELLENTMEAMENSMAQRSDLLELDCQL 76

  Fly   412 TQDAQVVVYHDFVLRFMLQRMPSFEDLLE----NQDLLIFAYENL----NKLML------LAMGG 462
            |:|..|||.||             |:|..    |:|:....:|:|    .||.:      .|.|.
Human    77 TRDRVVVVSHD-------------ENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGS 128

  Fly   463 SKR----KDL--------IAVPLEAFSYDQLKEV 484
            .:|    :||        ::|.::..:.:.::|:
Human   129 DRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREI 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888
		GDPD_GDE5	368..684	CDD:176549	34/143 (24%)
		GDPD	372..685	CDD:281062	34/139 (24%)
GDPD3	NP_077283.2	GDPD_GDE4	13..310	CDD:176553	38/164 (23%)
GDPD3	NP_077283.2	GDPD	44..301	CDD:281062	34/139 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900