DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3942 and gde1

DIOPT Version :9

Sequence 1:	NP_650171.2	Gene:	CG3942 / 41489	FlyBaseID:	FBgn0038008	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_956537.1	Gene:	gde1 / 393213	ZFINID:	ZDB-GENE-040426-881	Length:	333	Species:	Danio rerio

Alignment Length:	347	Identity:	71/347 - (20%)
Similarity:	120/347 - (34%)	Gaps:	107/347 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 IGHKGSGNTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQLTQDAQVVVYHDFVLRFMLQRMPS 434
            :.|:|.|:.       ..|||:...:.|....|..||:|::.|.|...::.||
Zfish    70 VAHRGGGHD-------APENTIAAIRAASENGATGVELDLEFTADGVPILMHD------------ 115

  Fly   435 FEDLLENQDLLIFAYENLNKLMLLAMGGSKRKDLIAVPLEAFSYDQLKEVKVLRFAGSKGCDKSC 499
                 |..|........||||:.     |:.:.|.|.....||.         ||.|.|
Zfish   116 -----ETVDRTTNGSGPLNKLLF-----SELRKLDAAAKHRFSD---------RFRGEK------ 155

  Fly   500 DRMLLEQRPFPLLLDLLDEENLPVDMGFLIEIK-WPQMTNMRRWESGSFKPTFDRNFYVDTILEI 563
                     .|.|.:.: ||.:...:....::| .|...      :.:.|..|.:       ..:
Zfish   156 ---------VPTLQEAV-EECIKHQLTIYFDVKGHPDEA------AAALKELFRK-------YPV 197

  Fly   564 VLNKAGKRRIVFCSFDADICAMVRFKQ---NVYPVTLLLEDPHSPVQYADQRVSVQDVAVRFCNS 625
            :.|.:     :.|||:..:  :.|.:|   ||  ||.|...|.|..::.|.       ..||.::
Zfish   198 LYNTS-----IVCSFEPKV--IYRMRQADPNV--VTALTHRPWSLSRFGDG-------TPRFSST 246

  Fly   626 -----LEFLGLTL---HANSLLNKPSTMAYLHQINL---DAFVY----GSSTIDLEIRNKLKKHG 675
                 ::.|.:.|   |.:.|.|.....|:|.|.|.   |...|    |...:...:...::|.
Zfish   247 WKQHWMQVLDVLLDWAHHHLLWNLCGVSAFLVQKNFISPDYVQYWAARGVEVVGWTVNTAVEKQ- 310

  Fly   676 VLGIIYDRLDQLDQVGEELEGD 697
                .|.:|.:::.:.:.|..|
Zfish   311 ----YYQQLLKINYITDSLVED 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888
		GDPD_GDE5	368..684	CDD:176549	68/332 (20%)
		GDPD	372..685	CDD:281062	68/331 (21%)
gde1	NP_956537.1	GDPD_GDE1	70..325	CDD:176515	69/342 (20%)
gde1	NP_956537.1	GDPD	72..323	CDD:281062	69/338 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900