Protein Alignment CG3942 and gde1

DIOPT Version :10

• Sequence 1: NP_650171.2
• Gene: CG3942 / 41489
• FlyBaseID: FBgn0038008
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_001417947.1
• Gene: gde1 / 2543677
• PomBaseID: SPAPB1E7.05
• Length: 1135
• Species: Schizosaccharomyces pombe
• Alignment Length: 708
• Identity: 162/708 - (22%)
• Similarity: 259/708 - (36%)
• Gaps: 200/708 - (28%)

  Fly    51 SLNGNEYVAISGNCPSLGNWDPKEVYI-------LAKNDCISCLCNCRQFEAS-------LEIPR 101
            ||.|::.|.:||..||.....|..|..       |:|||  :...|.....:|       ::|||
pombe   567 SLQGDDAVYVSGRSPSFAASRPSSVDFMSQSTDSLSKND--TTASNGSMTPSSSQNNSVIIDIPR 629

  Fly   102 NIDIHY----RYCVV-IHDPE---TDEVYIRFWESQLYPRVIRTCQNMLKNCDVFGKPHD----- 153
            :   |:    ..|:. :.:|:   .|.:::.:..:|         :|..:..:....|::
pombe   630 S---HFDNAGEVCLENLAEPDEIADDSIHLHYDAAQ---------ENSPQPVNGSSPPYELVFVT 682

  Fly   154 --DDEANQVDRGWATTETIVHL-----KIFNAPFCWQRQKPRLLYVHVQPMFEVPENPCNEPANP 211
              .:||         |.||..|     ||.....|........|..|:|.:         :|..|
pombe   683 RNTEEA---------TITIDLLANRSHKILGRTVCCLTSLVSDLGNHMQSL---------KPLAP 729

  Fly   212 IKMVSSQTRLSRYLSTREIKAGNQYLQLAQVEVTNLCVQNALAAQQRFGARCGPKDMELFHCSIA 276
            :.::||:|       .:.|...|..:.:::|.|           ..||.:..|          |:
pombe   730 LPLLSSKT-------LKPIAHVNADVLISKVTV-----------DDRFSSNDG----------IS 766

  Fly   277 FPEETLYRLDLYTYAHKAGYDEPPYHYGYGFLMPDQLLGTEGSARVKITCASTHRPLMEMCVRYL 341
            .|                                  .|..|..:.|..|......
pombe   767 TP----------------------------------ALSLEAVSNVSRTALEDAE---------- 787

  Fly   342 IIRPLPNFRCDLSHSYERYWRKNRLCMNIGHKGSGN------TYRLGSDVVRENTLYGFKQAVLA 400
              |.|.......|.|    .:.|.:.: |||:|.|.      :.:||     ||||..|.:|...
pombe   788 --RSLHKSATTTSES----GKSNGVAV-IGHRGLGKNQPDRLSLQLG-----ENTLQSFIKAADL 840

  Fly   401 NADMVEMDVQLTQDAQVVVYHDFVL---------------RFM-LQRMPSFEDLLENQDLLIFAY 449
            .|..||:|||:|:|...||||||::               :|: ....|| |::.::      |.
pombe   841 GASYVELDVQMTKDMVPVVYHDFIVNETGTDAQVHSLTLEQFLGASHSPS-EEIKDD------AS 898

  Fly   450 ENLNKLMLLAMGGSKRKDLIAVPLEAFSYDQLKEVKVLRFAGSKGCDKSCDRMLLEQRPFPLLLD 514
            :...|....|...|.......|....|:.:..: :|...:.|:......|       .||..|.|
pombe   899 DIQQKRRPRAYSSSFTPSGSQVNFGEFAEENAR-LKPKVYKGNALGHTIC-------APFTTLKD 955

  Fly   515 LLDEENLPVDMGFLIEIKWPQMTNMRRWESGSFKP-TFDRNFYVDTILEIVLNKAGKRRIVFCSF 578
            :|.|  :|..:|..:|.|:|.::..   |.....| .:|.||||||||.|:....|||:.:|.||
pombe   956 VLKE--VPQSVGLNVEFKYPMLSEA---EEEKLLPIAYDYNFYVDTILSIIKKYGGKRKYIFSSF 1015

  Fly   579 DADICAMVRFKQNVYPVTLLLEDPHSPVQYADQRVSVQDVAVRFCNSLEFLGLTLHANSLLNKPS 643
            :.|||.::..| :..||..|.|.  ......|.|.:....|::|.:...|||:......|:..|.
pombe  1016 NPDICILLSLK-STNPVLFLTEG--GTAYRTDVRAASLRQALKFASQWSFLGIVSACEPLIMCPR 1077

  Fly   644 TMAYLHQINLDAFVYGSSTIDLEIRNKLKKHGVLGIIYDRL----DQLDQVGEELEGD 697
            .:..:.|:.|..:.||....|::...:..:.||..:|.|.:    ..|:|..|.||.|
pombe  1078 LIKAVKQLGLSCYTYGVLNNDVDNVRRQVRFGVDAVIVDNVLAIRRALNQYDESLESD 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888	28/141 (20%)
		GDPD_GDE5	368..684	CDD:176549	95/338 (28%)
gde1	NP_001417947.1	SPX	2..143	CDD:269894
		ANKYR	<354..532	CDD:440430
		ANK repeat	357..382	CDD:293786
		ANK repeat	395..423	CDD:293786
		ANK repeat	425..456	CDD:293786
		ANK repeat	458..490	CDD:293786
		GDPD_YPL110cp_fungi	805..1127	CDD:176548	96/350 (27%)