DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3942 and GDPD4

DIOPT Version :9

Sequence 1:	NP_650171.2	Gene:	CG3942 / 41489	FlyBaseID:	FBgn0038008	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	XP_011543136.1	Gene:	GDPD4 / 220032	HGNCID:	24849	Length:	649	Species:	Homo sapiens

Alignment Length:	318	Identity:	67/318 - (21%)
Similarity:	117/318 - (36%)	Gaps:	112/318 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 GHKGSGNTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQLTQDAQVVVYHDFVLRFMLQRMPSF 435
            ||:|:.   .||.    |||:..|::||...|..:|.|:.|:.|....:.|||.|:    |..:.
Human   228 GHRGAP---MLGP----ENTMMSFEKAVEHGAHGLETDIHLSYDHVPFLMHDFDLK----RTTNI 281

  Fly   436 -----EDLLENQDLLIFAYENLNKLMLLAMGGSKRKDLIAVPLEAFSYDQLKEVKVLRFAGSKGC 495
                 |...||.     |:.|.:.|..|..|    |..:...|..| |:    :|.|
Human   282 GEVQPESACENP-----AFFNWDFLSTLNAG----KWFVKPELRPF-YN----MKPL-------- 324

  Fly   496 DKSCDRMLLEQRPFPLLLDLL---DEENLPVDMGFLIEIKWPQMTNMRRWESGSFKPTFD----- 552
             ...|:.....:..|.|.|||   ::|.     .|:|                     ||
Human   325 -SEADKERARNQSIPTLADLLTLAEKER-----KFVI---------------------FDLHRPP 362

  Fly   553 -----RNFYVDTILEIVLNKAGKRRIVFC--SFDADICAMVRFKQNVYPVTLLLEDPHSPVQYAD 610
                 |:.:|..::.::|....::.::|.  :.|.      ::.::|.|          ..|:..
Human   363 PKHPLRHTFVRQVVSVILASKIEQHLIFWLPAHDR------QYVRSVAP----------GFQHVG 411

  Fly   611 QRVSVQDVAVR------------FCNSL-EFLGLTLHAN-SLLNKP--STMAYLHQIN 652
            :.||::.:|..            |.|.| ::....:|.| ..:|:|  .::|:..:||
Human   412 RLVSIETLAKNNISIINVDYKKLFPNGLRDYKAANIHINVYTVNEPWLFSLAWCSRIN 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3942	NP_650171.2	CBM20_Prei4	44..164	CDD:99888
		GDPD_GDE5	368..684	CDD:176549	67/318 (21%)
		GDPD	372..685	CDD:281062	66/317 (21%)
GDPD4	XP_011543136.1	PI-PLCc_GDPD_SF	205..517	CDD:301322	67/318 (21%)
GDPD4	XP_011543136.1	UgpQ	223..482	CDD:223657	67/318 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900