DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a3 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	132/521 - (25%)
Similarity:	222/521 - (42%)	Gaps:	81/521 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTFQLLLAVGVCFWIYF------LWSRRRLYMMHFK---IPGPMGLPILGIAFEY-LITYKRKM 55
            |..|.:|  |.|.|::.|      :|...|: ..|||   :.||......|.:.|. .:|.:.|.
plant     1 MAVFFIL--VLVFFFLVFRFIYSNIWVPWRI-QSHFKKQSVTGPSYRIFSGNSGEVSRLTAEAKS 62

  Fly    56 S--------------IRTKYMD---IYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIF 103
            .              :...|.:   :||.|.|.|.|..|.|.|.||::..|...:....:|  |.
plant    63 KPIPSGRNPHEFVHRVAPHYHEWSRVYGKTFLYWFGSKPVVATSDPRLIREALTTGGSFDR--IG 125

  Fly   104 SKPVNSCT-GDGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK- 166
            ..|::... ..||..|...:|...|:....||....|..::|...:....|:...:.:...||:
plant   126 HNPLSKLLYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQMVTSTMMLMEKWEDMRNGGEEI 190

  Fly   167 --KVRDDIVRWSFRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVM---NVLLP---FTHNK 223
              :|..::...|..:.::|..|..|:     :...:.:..|..|::..:   :|.:|   |..:|
plant   191 ELEVHKEMHNLSAEMLSRTAFGNSVE-----EGKGIFELQERMMRLFYLVRWSVYIPGFRFFPSK 250

  Fly   224 IFSTLGGFETQKALAKSNVNKMI---GTIVDKKLMTKPESGS--QPEITSVINKAIELHRNGEMS 283
            ....:...|.|   .:.::.|:|   .|.|:|       ||:  |..::...|      :||:..
plant   251 TNREIWRIEKQ---IRVSILKLIENNKTAVEK-------SGTLLQAFMSPYTN------QNGQEE 299

  Fly   284 R---EEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEV-TYDDL 344
            :   |||..||.:|..||.|||.:.:...|:||||..|.|:...:   |:..|.|...: |.|.|
plant   300 KLGIEEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEWQNIARE---EVICVLGQTGLPTLDIL 361

  Fly   345 QRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSS 409
            |.:..|..::||||||.|......|:|::..:|.. :.||.|..:.:.:.|.|.:::.||.|...
plant   362 QDLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGD-LDIPAGTQLYLSVVAMHHDKETWGDDAEE 425

  Fly   410 FNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILR--NCKVSTSFRYEDLEF 472
            |||..|....   :.....:||..|.|.|:|....:..:|..|:.||:  :.::|.|:.:..:.|
plant   426 FNPRRFEDPK---KQSALLVPFGLGPRTCVGQNLAVNEAKTVLATILKYYSFRLSPSYAHAPVLF 487

  Fly   473 V 473
            |
plant   488 V 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	116/468 (25%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	124/494 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060