DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a3 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	129/531 - (24%)
Similarity:	211/531 - (39%)	Gaps:	102/531 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTFQLLLAVGVCFWIYFLWS-------RRRLYMMHFK---IPGPMGLPILGIAFEYLITYKRKM 55
            :.|..||..|.:.|.:..:|.       |..:....||   |.||          :|.|.|....
plant     4 ISTINLLTIVLLLFVVSKIWKACWILLLRPLMLSKRFKKQGISGP----------KYKILYGNLS 58

  Fly    56 SIRT--------------------------KYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLS- 93
            .|:.                          ::|..||.|.|.|.|..|.:...:.::|:::..|
plant    59 EIKKMKKEADLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSK 123

  Fly    94 ------PECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRKNLNPAFKQNVLLSF--------LP 144
                  |  :.|..:|     ...|.||..::...|:..|:.|||||..:.|.:.        |.
plant   124 FGFTIIP--VKRPEVF-----ILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLR 181

  Fly   145 IFNSEAKTLVAFLDSLVGQGEKKVRDDIVRWSFRIATQTTVGTDVKKDASFKNDSVLKSYETFMK 209
            ||....|..        ..||..::.:|.: .|...|...:.|.....:..:...:.:|.....|
plant   182 IFEEWRKQR--------RNGEVLIKIEISK-EFHKLTADIIATTAFGSSYAEGIELCRSQTELEK 237

  Fly   210 IIV---MNVLLPFTHNKIFST-LGGFETQKALAKSNVNKMIGTIVDKKLMTKPES-GSQPEITSV 269
            ..:   .||.:|.|......| |..:|..|     .|...|..|:|.:|.:|.:: |...::..|
plant   238 YYISSLTNVFIPGTQYLPTPTNLKLWELHK-----KVKNSIKRIIDSRLKSKCKTYGYGDDLLGV 297

  Fly   270 I---NKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELF 331
            :   .|:.|..|  :|..:|:..||.:|..|...||...:....:||::   ||....:..:|:|
plant   298 MLTAAKSNEYER--KMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSL---HQGWQEKLREEVF 357

  Fly   332 PVAGDFEV-TYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFA 395
            ...|..:: ..|...::..:..|:.|:|||...|....||..:|.::.. :.||||..|.|.:..
plant   358 NECGKDKIPDTDTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGH-LEIPKGTSIIIPLLK 421

  Fly   396 THRNRDHWGTDPSSFNPDHFLPDNVRDR---HPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILR 457
            .||::..||.|...|||..|  :|...:   ||.|.:|||.|.|.||...:.::.:|..|:.||:
plant   422 MHRDKAIWGEDAEQFNPLRF--ENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMILQ 484

  Fly   458 NCKVSTSFRYE 468
            ..::|.|..|:
plant   485 QFQLSLSPEYK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	116/482 (24%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	128/526 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970