Protein Alignment Cyp313a3 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 137/494 - (27%)
• Similarity: 215/494 - (43%)
• Gaps: 61/494 - (12%)

  Fly     6 LLLAVG-------VCFWIYFLWSR-RRLYMMHFKIP-------GPMGLPILGIAFEYLITYKRKM 55
            |||.||       |..|.|..:.. |||..  |..|       |..||         :...:..|
Human    21 LLLLVGGSWLLARVLAWTYTFYDNCRRLQC--FPQPPKQNWFWGHQGL---------VTPTEEGM 74

  Fly    56 SIRTKYMDIYGSTCLVWVGPT-PFVITRDPKIAEEI-FLSPECLNRSSIFSKPVNSCTGDGLLSL 118
            ...|:.:..|.....:|:||| |.:|...|.|...| ..|.....:..||...:....|||||..
Human    75 KTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLS 139

  Fly   119 EASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIVRWSFRIATQT 183
            ...||...|:.|.|||..|:|..::.|||.....:......|..:|..::  |:    |...:..
Human   140 GGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARL--DM----FEHISLM 198

  Fly   184 TVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKI--------FSTLGGFETQKALAKS 240
            |:.:..|...||:::...|..|....|:.::..:...:.:|        :.|..|...::|.  .
Human   199 TLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRAC--H 261

  Fly   241 NVNKMIGTIVDKKLMTKPESGSQPEITSVINKA------------IELHRNG-EMSREEVQSECC 292
            .|:.....::.::..|.|..|....:.   |||            :....:| |:|.|::::|..
Human   262 LVHDFTDAVIQERRCTLPTQGIDDFLK---NKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEAD 323

  Fly   293 SFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNET 357
            :|:....:||...:...|..||..||:|:...||::||.......|:.:|||.::.||...:.|:
Human   324 TFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKES 388

  Fly   358 LRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRD 422
            |||.|.||...|...:||.|..|.|||||:...|:|...|.|...| .||..::|..|..:|:::
Human   389 LRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRFDQENIKE 452

  Fly   423 RHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKV 461
            |.|.|:||||.|.|||||..:.:...|:.|:..|.:.::
Human   453 RSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	118/419 (28%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	121/430 (28%)