Protein Alignment Cyp313a3 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 486
• Identity: 136/486 - (27%)
• Similarity: 212/486 - (43%)
• Gaps: 59/486 - (12%)

  Fly     1 MDTFQLLLAVGVCFWIYFLWSRRRLYMMHFK--IPGPMGLPILGIAFEYLITYKRKMSIRTKYMD 63
            :||:.||..:.|..:.|    ..|.:.:..|  ||||..||.||....|   ||.......:..:
Mouse     9 LDTWVLLAIILVLLYRY----GTRTHGLFKKQGIPGPKPLPFLGTVLNY---YKGLWKFDMECYE 66

  Fly    64 IYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSK-----PVNSCTGDGLLSLEAS-- 121
            .||.|..::.|..|..:..||::.:.: |..||.   |:|:.     ||      |::|...|
Mouse    67 KYGKTWGLFDGQMPLFVITDPEMIKNV-LVKECF---SVFTNRREFGPV------GIMSKAISIS 121

  Fly   122 ---KWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIV-RWSFRIATQ 182
               :|...|..|:|.|....|....|:.......||.:|.....:|:.....|:: .:|..:.|.
Mouse   122 KDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITS 186

  Fly   183 TTVGTDV-----KKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQK---ALAK 239
            |:.|.:|     .:|...:....:...:.|..::...||.||. ..::..|......|   ...|
Mouse   187 TSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFL-TPVYEMLNICMFPKDSIEFFK 250

  Fly   240 SNVNKMIGTIVDKKLMTKPESGSQPEITSVINKAIELHRNGE-------MSREEVQSECCSFVVA 297
            ..||:|..:.:|.|         |......:...:..|.|.:       :|..|:.::...|:.|
Mouse   251 KFVNRMKESRLDSK---------QKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFA 306

  Fly   298 AFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIP 362
            .:|||..|:...|..||..|:.|..:.:|:.|..|  .....|||.:..|.:|:.|:||||||.|
Mouse   307 GYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLP--NKAPPTYDTVMEMEYLDMVLNETLRLYP 369

  Fly   363 SVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYA 427
            ......|...:|..| :||.||||..:.|..:|.|.:..|| .:|..|.|:.|..:|.....||.
Mouse   370 IGNRLERFCKKDVEL-NGVYIPKGSTVMIPSYALHHDPQHW-PEPEEFQPERFSKENKGSIDPYL 432

  Fly   428 YIPFSKGRRNCIGWKYGLMSSKLALSKILRN 458
            |:||..|.|||||.::..|:.||||:|:::|
Mouse   433 YMPFGIGPRNCIGMRFAFMTMKLALTKVMQN 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	116/419 (28%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	117/421 (28%)