DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a3 and Cyp313b1

DIOPT Version :9

Sequence 1:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	167/529 - (31%)
Similarity:	278/529 - (52%)	Gaps:	80/529 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSIRT--KYMD----I 64
            ||||     |:||||||||.|.:.:::.||:|.|::|:..:       .|:..|  :|||    .
  Fly    11 LLLA-----WLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQ-------MMNPETFLQYMDGLSRQ 63

  Fly    65 YGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRKN 129
            :.:..:.|:|.:.|:...||...|:|..|..|.|:.. |.:.::|..||||.:..:.:|...|:.
  Fly    64 FKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGD-FYRFMSSAIGDGLFTSSSPRWHKHRRL 127

  Fly   130 LNPAFKQNVLLSFLPIFNSEAKTLVAFLD-SLVGQGEK-KVRDDIVRWSFRIATQTTVGTDVKKD 192
            :||||.:.:|.:||||||:||:.|:..|: ..|..|:: ::...:.:.....|.|||:|    |.
  Fly   128 INPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAACQTTMG----KK 188

  Fly   193 ASFKNDS---VLKSYETFMKIIVMNVLLPFTH-NKIFSTLGGFETQKALAKSNVNKMIGTI---V 250
            .:|::|.   :.|:|....::.|..:|.|:.: :.|:...|.|..|:        |::|.:   :
  Fly   189 MNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQ--------KVVGILFGFI 245

  Fly   251 DKKLMTKPESGSQPEITSVI------------------NKAIELHR------NGEMSREEVQSEC 291
            ::.|        :| |.||:                  :|||.:.:      .|::|.::|:.|.
  Fly   246 EQLL--------EP-IVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDEA 301

  Fly   292 CSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNE 356
            ...:.|.||||...:|..::.|||.|.:|:.:::||....|.:||  :..:.|||:.:.|.|:||
  Fly   302 NVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGD--INLEQLQRLEYTEMVINE 364

  Fly   357 TLRLIPSVPFTPRETIRDFRLSSG---VVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPD-HFLP 417
            .:||...||...|...:|.:|..|   .:||:|..|||||:...|:...||....::||| ||..
  Fly   365 AMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGL 429

  Fly   418 DNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQ 482
            |:.: ||.:|::||:||.|.|||::|..|..||.|::|.|:.::||..|.|:|....||.::|..
  Fly   430 DSPQ-RHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLVKGNISLKLKD 493

  Fly   483 SPGLEFHRR 491
            .|.....||
  Fly   494 YPLCRVERR 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	142/472 (30%)
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	142/472 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450086
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D28972at7147
OrthoFinder	1	1.000	-	-		FOG0008559
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000