Protein Alignment Cyp313a3 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001386630.1
• Gene: Cyp46a1 / 362782
• RGDID: 1306605
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 117/481 - (24%)
• Similarity: 214/481 - (44%)
• Gaps: 65/481 - (13%)

  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSIRTKYMDI------ 64
            :|||.|:|  ..|:...|..|.   .||||.....|.....|.  :|:..:......|:
  Rat    12 VLLAFGLC--CTFVHRARSRYE---HIPGPPRPSFLLGHLPYF--WKKDEACGRVLQDVFLDWAK 69

  Fly    65 -YGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGD-----GLLS-LEASK 122
             ||....|.|.....||...|:..::..:|.: .|:.|...:.:.:..|:     ||:| .:..:
  Rat    70 KYGPVVRVNVFHKTSVIVTSPESVKKFLMSTK-YNKDSKMYRAIQTVFGERLFGQGLVSECDYGR 133

  Fly   123 WVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLV-GQGEKKVRDDIVRWSFRIATQTTVG 186
            |..:|:.::.||.::.|:|.:..||.:|:.|:..|::.. ||....::|        :.|..|:
  Rat   134 WYKQRRVMDLAFSRSSLVSLMGTFNEKAEQLMEILEAKADGQTPVSMQD--------MLTCATI- 189

  Fly   187 TDVKKDASFKNDSVL-----KSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQKALAKSNVN--K 244
             |:...|:|..::.:     |.....:|:::..:  ..:.|.:...:.|...|....:.::.  :
  Rat   190 -DILAKAAFGMETSMLLGAQKPLSQAVKVMLEGI--SASRNTLAKFMPGKRKQLREIRESIRLLR 251

  Fly   245 MIGT--IVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVY 307
            .:|.  :..::...|.......:|.:.|.||.|    |....|.:.....:|.:|..||:.:.:.
  Rat   252 QVGKDWVQRRREALKRGEDVPADILTQILKAEE----GAQDDEVLLDNFVTFFIAGHETSANHLA 312

  Fly   308 HALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPR--- 369
            ..::.|:..||....:..|:.|:  |.....:.|:||.|:.:|.:|:.|:|||.|....|.|
  Rat   313 FTVMELSRQPEIVARLQAEVDEV--VGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLE 375

  Fly   370 -ETIRDFRLSSGVVIPKGVGIGIDIFATH--RNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPF 431
             ||:.|     ||.:|....:   :|:|:  ...|.:..||.:||||.|.|...:.|  :.|.||
  Rat   376 EETLID-----GVRVPGNTPL---LFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPF 430

  Fly   432 SKGRRNCIGWKYGLMSSKLALSKILR 457
            |.|.|:|||.::..|..|:.::|:|:
  Rat   431 SLGHRSCIGQQFAQMEVKVVMAKLLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	100/414 (24%)
Cyp46a1	NP_001386630.1	CYP46A1-like	61..484	CDD:410706	102/425 (24%)