DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a3 and Cyp4ae1

DIOPT Version :9

Sequence 1:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	104/441 - (23%)
Similarity:	203/441 - (46%)	Gaps:	25/441 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 IPGPMGLPILGIAFEYLITYKRKMSIR-TKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPE 95
            :|....:|:||.|::........:..: .:|:..:|.:.:..|.....::|.:|:..:.:.....
  Fly    34 VPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQH 98

  Fly    96 CLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSL 160
            .|.:.:::. .:....|||||.....:|...||.:.|.|..::|..|:.:|:.::..||..|.:|
  Fly    99 QLKKGTMYF-ALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTL 162

  Fly   161 -VGQGEKKVRDDIVRWSFRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLP---FTH 221
             .|.....:...:...:..|.|:|.:|.:|  ||...:..|:.:.:....|:....:.|   |.|
  Fly   163 SYGNEVVNIYPLVGLAALDIITETAMGVNV--DAQGADSEVVHAVKDLTNILATRFMRPHLLFPH 225

  Fly   222 NKIFSTLGGFETQKALAKSNVNKMIGTIVDKKLMTKPESGSQPEIT---SVINKAIELHRNGE-M 282
            ........||..|:| ....:::....|::::........:|.:.|   ::::..:....:|: :
  Fly   226 LFRLCWPSGFRKQQA-GVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPL 289

  Fly   283 SREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELK-----ELFPVAGDFEVTYD 342
            :.::::.|..:|:....:||...|...|.||:.....|..:::||:     :||.     .|...
  Fly   290 TDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFR-----GVILS 349

  Fly   343 DLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDP 407
            |...:.:|..||.|:|||.|.:|...|...:|..:..| .||.|..:.:.::...|:...: |||
  Fly   350 DFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG-YIPVGTNVVVLLWQLLRDEAIF-TDP 412

  Fly   408 SSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRN 458
            ..|.|:..|.:......||:|||||.|.|||||.|:.|:..|..::|::|:
  Fly   413 LVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRH 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	104/440 (24%)
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	104/440 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.870