Protein Alignment Cyp313a3 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 125/525 - (23%)
• Similarity: 200/525 - (38%)
• Gaps: 107/525 - (20%)

  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGP-----MGLPILGIAFEYLITYKRKMSIRTKYMDIY 65
            |:|...|.|::...|..:.|.    |.|..     .|..:....|:.::|:..|          :
  Rat    29 LVLFKAVQFYLRRQWLLKALE----KFPSTPSHWLWGHDLKDREFQQVLTWVEK----------F 79

  Fly    66 GSTCLVWV-GPTPFVITRDPKIAEEIF--LSPECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRR 127
            ...||.|: |....|:..||...:.:.  ..|:........:..:.|.||.|||.|...||....
  Rat    80 PGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKASGIYQFLAPWIVSGTGYGLLLLNGKKWFQHW 144

  Fly   128 KNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK---------KVRDDIVRWSFRIATQT 183
            :.|.|||...:|..::.|.......::...:.|..|...         ...|.:::.:|  :.|.
  Rat   145 RMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAF--SHQG 207

  Fly   184 TVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGG------------------ 230
            :|..||      .:.|..|:.|....:....|...|..|.|...:..
  Rat   208 SVQLDV------NSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDG 266

  Fly   231 ------------FETQKALAKSNVNKMIGTIVDKKLMTKPESGSQPEITSVINKAIELHRNGEMS 283
                        .|.|||..|.:::     .:|..|..|.|.|.                  .:|
  Rat   267 VIKMRKAQLQNEEELQKARKKRHLD-----FLDILLFAKMEDGK------------------SLS 308

  Fly   284 REEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGD-FEVTYDDLQRM 347
            .|::::|..:|:....:||...:......||..||||:...:|::.   :.|| ..||:|.|.::
  Rat   309 DEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQS---ILGDGTSVTWDHLDQI 370

  Fly   348 VFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNP 412
            .:....:.|.|||.|.||...||.........|..||||:...|.|:..|.|..:| .:|..|:|
  Rat   371 SYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDP 434

  Fly   413 DHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIG 477
            ..|.||:  .||.:||:|||.|.|||||.::.:...|:|::        .|..|:|.|.....|.
  Rat   435 SRFSPDS--PRHSHAYLPFSGGARNCIGKQFAMNELKVAVA--------LTLLRFELLPDPTRIP 489

  Fly   478 MELAQ 482
            :.:|:
  Rat   490 VPMAR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	113/460 (25%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	116/481 (24%)